Accessory Toxins of Vibrio Pathogens and Their Role in Epithelial Disruption During Infection

D Pérez-Reytor, V Jaña, L Pavez, P Navarrete… - Frontiers in …, 2018 - frontiersin.org
Gastrointestinal episodes associated with Vibrio species have been rising worldwide in the
last few years. Consequently, it is important to comprehend how occurs the production of …

Factors that influence climate change-related mortality in the United States: an integrative review

R McDermott-Levy, M Scolio, KM Shakya… - International Journal of …, 2021 - mdpi.com
Global atmospheric warming leads to climate change that results in a cascade of events
affecting human mortality directly and indirectly. The factors that influence climate change …

Microbiological assessment of marine and estuarine ecosystems using fecal indicator bacteria, Salmonella, Vibrio and antibiotic resistance pattern

A Chahouri, N Radouane, B Yacoubi, A Moukrim… - Marine Pollution …, 2022 - Elsevier
Marine and estuarine environments are often affected by microbiological contamination that
adversely affects their use and severely impacts human health. To examine the influence of …

Vibrio vulnificus PlpA facilitates necrotic host cell death induced by the pore forming MARTX toxin

C Cho, S Choi, MH Kim, BS Kim - Journal of Microbiology, 2022 - Springer
Opportunistic pathogen Vibrio vulnificus causes severe systemic infection in humans with
high mortality. Although multiple exotoxins have been characterized in V. vulnificus, their …

Genetic divergence of Vibrio vulnificus clinical isolates with mild to severe outcomes

K Kling, SA Trinh, SA Leyn, DA Rodionov, ID Rodionov… - Mbio, 2022 - Am Soc Microbiol
The marine bacterium Vibrio vulnificus infects humans via food or water contamination,
leading to serious manifestations, including gastroenteritis, wound infections, and septic …

The modes of action of MARTX toxin effector domains

BS Kim - Toxins, 2018 - mdpi.com
Many Gram-negative bacterial pathogens directly deliver numerous effector proteins from
the bacterium to the host cell, thereby altering the target cell physiology. The already well …

Vibrio-infecting bacteriophages and their potential to control biofilm

A Cevallos-Urena, JY Kim, BS Kim - Food Science and Biotechnology, 2023 - Springer
The emergence and spread of antibiotic-resistant pathogenic bacteria have necessitated
finding new control alternatives. Under these circumstances, lytic bacteriophages offer a …

Makes caterpillars floppy-like effector-containing MARTX toxins require host ADP-ribosylation factor (ARF) proteins for systemic pathogenicity

Y Lee, BS Kim, S Choi, EY Lee… - Proceedings of the …, 2019 - National Acad Sciences
Upon invading target cells, multifunctional autoprocessing repeats-in-toxin (MARTX) toxins
secreted by bacterial pathogens release their disease-related modularly structured effector …

Coordinated delivery and function of bacterial MARTX toxin effectors

PJ Woida, KJF Satchell - Molecular microbiology, 2018 - Wiley Online Library
Bacteria often coordinate virulence factors to fine‐tune the host response during infection.
These coordinated events can include toxins counteracting or amplifying effects of another …

Structural basis of inactivation of Ras and Rap1 small GTPases by Ras/Rap1-specific endopeptidase from the sepsis-causing pathogen Vibrio vulnificus

SY Jang, J Hwang, BS Kim, EY Lee, BH Oh… - Journal of Biological …, 2018 - ASBMB
Multifunctional autoprocessing repeats-in-toxin (MARTX) toxins are secreted by Gram-
negative bacteria and function as primary virulence-promoting macromolecules that deliver …