Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms
E Ahmadian, SM Hosseiniyan Khatibi… - Reviews in medical …, 2021 - Wiley Online Library
The novel coronavirus (SARS‐CoV‐2) has turned into a life‐threatening pandemic disease
(Covid‐19). About 5% of patients with Covid‐19 have severe symptoms including septic …
(Covid‐19). About 5% of patients with Covid‐19 have severe symptoms including septic …
Physiological and pathological regulation of ACE2, the SARS-CoV-2 receptor
Y Li, W Zhou, L Yang, R You - Pharmacological research, 2020 - Elsevier
The renin-angiotensin system (RAS) is crucial for the physiology and pathology of all the
organs. Angiotensin-converting enzyme 2 (ACE2) maintains the homeostasis of RAS as a …
organs. Angiotensin-converting enzyme 2 (ACE2) maintains the homeostasis of RAS as a …
Outcomes of patients with end-stage kidney disease hospitalized with COVID-19
Given the high risk of infection-related mortality, patients with end-stage kidney disease
(ESKD) may be at increased risk with COVID-19. To assess this, we compared outcomes of …
(ESKD) may be at increased risk with COVID-19. To assess this, we compared outcomes of …
[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
Factors leading to high morbidity and mortality of COVID‐19 in patients with type 2 diabetes
Abstract Coronavirus disease 2019 (COVID‐19) is a recent pandemic caused by severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a novel coronavirus. Diabetes …
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), a novel coronavirus. Diabetes …
[HTML][HTML] ACE2/ADAM17/TMPRSS2 interplay may be the main risk factor for COVID-19
D Zipeto, JF Palmeira, GA Argañaraz… - Frontiers in …, 2020 - frontiersin.org
The Coronavirus Disease 2019 (COVID-19) has already caused hundreds of thousands of
deaths worldwide in a few months. Cardiovascular disease, hypertension, diabetes and …
deaths worldwide in a few months. Cardiovascular disease, hypertension, diabetes and …
[HTML][HTML] COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …
[HTML][HTML] A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
It is not well understood why diabetic individuals are more prone to develop severe COVID-
19. To this, we here established a human kidney organoid model promoting early hallmarks …
19. To this, we here established a human kidney organoid model promoting early hallmarks …
[HTML][HTML] Classical renin-angiotensin system in kidney physiology
MA Sparks, SD Crowley, SB Gurley… - Comprehensive …, 2014 - ncbi.nlm.nih.gov
The renin-angiotensin system has powerful effects in control of the blood pressure and
sodium homeostasis. These actions are coordinated through integrated actions in the …
sodium homeostasis. These actions are coordinated through integrated actions in the …
[HTML][HTML] Potential role of ACE2 in coronavirus disease 2019 (COVID-19) prevention and management
M Liu, T Wang, Y Zhou, Y Zhao, Y Zhang… - Journal of translational …, 2020 - degruyter.com
COVID-19 is the current public health threat all over the world. Unfortunately, there is no
specific prevention and treatment strategy for this disease. We aim to explore the potential …
specific prevention and treatment strategy for this disease. We aim to explore the potential …