TNF-alpha production inhibitor comprising kavalactone as an active ingredient

Y Asakawa, S Okabe, M Yamada, Y Suma… - US Patent App. 11 …, 2006 - Google Patents
The present invention provides a TNF-C. production inhibi tor containing a kavalactone as
an active ingredient, which inhibitor has high safety, exerts an excellent effect of inhib iting …

TNF-α production inhibitor comprising kavalactone as an active ingredient

Y Asakawa, S Okabe, M Yamada, Y Suma… - US Patent …, 2003 - Google Patents
The present invention provides a TNF-C. production inhibi tor containing a kavalactone as
an active ingredient, which inhibitor has high safety, exerts an excellent effect of inhib iting …

TNF-α production inhibitor comprising kavalactone as an active ingredient

Y Asakawa, S Okabe, M Yamada, Y Suma… - US Patent …, 2007 - Google Patents
The present invention provides a TNF-C. production inhibi tor containing a kavalactone as
an active ingredient, which inhibitor has high safety, exerts an excellent effect of inhib iting …

Kava derived therapeutic compounds and methods of use thereof

C Xing, S Hecht, J Lu, P Upadhyaya, S Murphy… - US Patent …, 2021 - Google Patents
5495-5500 (1991). Peterson, LA, et al.,“Role of aldehydes in the toxic and mutagenic effects
of nitrosamines”, Chem Res Toxicol 26, 1464-1473 (2013). Pittler, MH, et al.,“Efficacy of kava …