Y-box-binding protein 1 (YB-1) and its functions

IA Eliseeva, ER Kim, SG Guryanov… - Biochemistry …, 2011 - Springer
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …

Targeting the Y/CCAAT box in cancer: YB-1 (YBX1) or NF-Y?

D Dolfini, R Mantovani - Cell Death & Differentiation, 2013 - nature.com
The Y box is an important sequence motif found in promoters and enhancers containing a
CCAAT box–one of the few elements enriched in promoters of large sets of genes …

Y-box binding protein 1–a prognostic marker and target in tumour therapy

C Kosnopfel, T Sinnberg, B Schittek - European journal of cell biology, 2014 - Elsevier
Y-box binding protein 1 (YB-1) is a multifunctional protein involved in various cellular
processes including both transcriptional and translational regulation of target gene …

Transport proteins of the ABC family and multidrug resistance of tumor cells

AA Stavrovskaya, TP Stromskaya - Biochemistry (Moscow), 2008 - Springer
Some new data concerning the role of transport proteins of the ABC family in multidrug
resistance (MDR) of human tumor cells, and problems connected with regulation of these …

[HTML][HTML] Role of Y Box Protein-1 in cancer: As potential biomarker and novel therapeutic target

PK Maurya, A Mishra, BS Yadav, S Singh… - Journal of …, 2017 - ncbi.nlm.nih.gov
The Y-box binding protein (YB-1) is known to be a multifunctional transcription and
translation factor during expression of several proteins. It is a vital oncoprotein that regulates …

Y box binding protein 1 (YB-1) oncoprotein at the hub of DNA proliferation, damage and cancer progression

F Sangermano, A Delicato, V Calabrò - Biochimie, 2020 - Elsevier
The Y Box binding protein 1 (YB-1) belongs to the highly conserved Cold Shock Domain
protein family and is a major component of messenger ribonucleoprotein particles (mRNPs) …

Role of P-glycoprotein in evolution of populations of chronic myeloid leukemia cells treated with imatinib

TP Stromskaya, EY Rybalkina, SS Kruglov… - Biochemistry …, 2008 - Springer
Imatinib mesylate (imatinib) is a new generation preparation that is now successfully used
for treatment of cancer, particularly for chemotherapy of chronic myeloid leukemia (CML) …

YB-1 protein and multidrug resistance of tumor cells

A Stavrovskaya, T Stromskaya… - Current signal …, 2012 - ingentaconnect.com
Y-box binding protein 1 (YB-1) is a member of the large protein family with an evolutionarily
ancient coldshock domain. It is involved in the regulation of some global traits of malignancy …

Regulation of MDR1 gene expression in multidrug-resistant cancer cells is independent from YB-1

A Kaszubiak, A Kupstat, U Müller, R Hausmann… - Biochemical and …, 2007 - Elsevier
The MDR1 gene encoded transmembrane ABC-transporter MDR1/P-glycoprotein can
mediate the phenotype of multidrug resistance (MDR), a major obstacle in the clinical …

Connection between proliferation rate and temozolomide sensitivity of primary glioblastoma cell culture and expression of YB-1 and LRP/MVP

NI Moiseeva, OY Susova, AA Mitrofanov… - Biochemistry …, 2016 - Springer
Glioblastomas (GBL) are the most common and aggressive brain tumors. They are
distinguished by high resistance to radiation and chemotherapy. To find novel approaches …