Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Natural products (NPs) are secondary metabolites produced and used by organisms for
defending or adapting purposes. These molecules were naturally selected during thousands …

The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Natural products continue to provide a diverse and unique source of bioactive lead
compounds for drug discovery, but maintaining their continued eminence as source …

Although traditionally natural products have played an important role in drug discovery, in
the past few years most Big Pharma companies have either terminated or considerably …

Covering: up to 2020 The National Cancer Institute of the United States (NCI) has initiated a
Cancer Moonshot program entitled the NCI Program for Natural Product Discovery. As part …

Alkaloids are an important group of diversely distributed, chemically, biologically and
commercially significant natural products. This article suggests why now, with the presently …

Microbial natural products are the origin of most of the antibiotics on the market today.
However, research in antibiotics and natural products has declined significantly during the …

Natural products historically have been a rich source of lead molecules in drug discovery,
based on their capability to create unique and diverse chemical structures. However, it is …

While natural products or their derivatives and mimics have contributed around 50% of
current drugs, there has been no approach allowing front-loading of chemical space …