LIM kinase 1 (LIMK1) and LIM kinase 2 (LIMK2) are serine/threonine and tyrosine kinases
and the only two members of the LIM kinase family. They play a crucial role in the regulation …

Alternative splicing and polyadenylation represent two major steps in pre‐mRNA‐
processing, which ensure proper gene expression and diversification of human …

Simple Summary There are three subfamilies of human PDZ-LIM family proteins with a total
of 10 protein molecules, and PDZ-LIM family proteins serve as a class of scaffolding proteins …

LIM Kinases are important actors in the regulation of cytoskeleton dynamics by controlling
microtubule and actin filament turnover. The signaling pathways involving LIM kinases for …

Melanoma is the leading cause of skin cancer-related deaths, and current melanoma
therapies, including targeted therapies and immunotherapies, benefit only a subset of …

Triple negative breast cancer (TNBC) is an aggressive cancer, particularly prone to
metastasis and is associated with poor survival outcomes. The key to unravelling the …

Abstract Background The RNA N 6-methyladenosine (m6A) modification has become an
essential hotspot in epigenetic modulation. Serine–arginine protein kinase 1 (SRPK1) is …

Simple Summary Colorectal cancer is the second leading cause of cancer-related deaths
worldwide. The incidence of this cancer continues to rise, especially in developing countries …

Background Small cell lung cancer (SCLC) is a very malignant tumor with rapid growth and
early metastasis. Platinum-based chemo-resistance is the major issue for SCLC treatment …

Background Cancer is one of the leading causes of death worldwide. Early diagnosis can
significantly lower cancer-related mortality. Studies have shown that the lncRNA Forkhead …