Oesophageal cancer is a global health problem; in 2018 there were more than 572,000
people newly diagnosed with oesophageal cancer worldwide. There are two main …

Esophageal squamous cell carcinoma (ESCC) accounts for about 90% of the 456,000
incident esophageal cancers each year. Regions of high incidence include Eastern to …

Caspase-8 is a cysteine-aspartate specific protease that classically triggers the extrinsic
apoptotic pathway, in response to the activation of cell surface Death Receptors (DRs) like …

The incidence and mortality trends of oesophageal cancer are changing significantly across
the world with considerable heterogeneity between sex, histological types, ethnic patterns …

To identify common genetic variants that contribute to lung cancer susceptibility, we
conducted a multistage genome-wide association study of lung cancer in Asian women who …

Genome-wide association studies (GWAS) have previously identified 13 loci associated with
risk of chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL). To identify …

We conducted a joint (pooled) analysis of three genome-wide association studies (GWAS),,
of esophageal squamous cell carcinoma (ESCC) in individuals of Chinese ancestry (5,337 …

Aging populations face diminishing quality of life due to increased disease and morbidity.
These challenges call for longevity research to focus on understanding the pathways …

The DNA repair pathways help to maintain genomic integrity and therefore genetic variation
in the pathways could affect the propensity to develop cancer. Selected germline single …

Introduction Esophageal cancer is the eighth most common cancer worldwide and the sixth
leading cause of cancer-related deaths. As a significant cause of morbidity and mortality, its …