The timelines for developing vaccines against infectious diseases are lengthy, and often
vaccines that reach the stage of large phase 3 field trials fail to provide the desired level of …

The gram-negative bacterium Shigella is an enteric pathogen responsible for significant
morbidity and mortality due primarily to severe diarrhea and dysentery, mainly among …

Guide de surveillance des maladies non transmissibles dans les établissements: Cadre,
indicateurs et application fournit les indicateurs nécessaires pour le suivi des patients et des …

Enterotoxigenic Escherichia coli (ETEC) is one of the leading bacterial causes of diarrhoea,
especially among children in low-resource settings, and travellers and military personnel …

Background Vaccine impact and cost-effectiveness models have mostly focused on acute
burden. Shigella-attributable moderate-to-severe diarrhoea has been shown to be …

Shigella is the leading bacterial cause of diarrhoea and the second leading cause of
diarrhoeal mortality among all ages. It also exhibits increasing levels of antibiotic resistance …

Background No licensed human vaccines are available against enterotoxigenic Escherichia
coli (ETEC), a major diarrhoeal pathogen affecting children in low-and middle-income …

Background Linear growth is an important outcome of child development with implications
for economic productivity. Enteric infections, particularly Shigella, have been linked to linear …

The development and licensure of a safe and highly efficacious Shigella vaccine has been a
priority in international public health circles for decades and would represent a great …

Background Shigella is the leading bacterial cause of diarrheal mortality in children and can
cause long-term effects on growth and development. No licensed Shigella vaccines …