[HTML][HTML] NAFLD: mechanisms, treatments, and biomarkers

F Nassir - Biomolecules, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), recently renamed metabolic-associated fatty liver
disease (MAFLD), is one of the most common causes of liver diseases worldwide. NAFLD is …

Non-alcoholic fatty liver disease: An overview of risk factors, pathophysiological mechanisms, diagnostic procedures, and therapeutic interventions

SH Gerges, SA Wahdan, DA Elsherbiny… - Life Sciences, 2021 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is a disorder of excessive fat accumulation in the
liver, known as steatosis, without alcohol overconsumption. NAFLD can either manifest as …

[PDF][PDF] Effect of alternate day fasting combined with aerobic exercise on non-alcoholic fatty liver disease: A randomized controlled trial

M Ezpeleta, K Gabel, S Cienfuegos, F Kalam, S Lin… - Cell metabolism, 2023 - cell.com
Innovative non-pharmacological lifestyle strategies to treat non-alcoholic fatty liver disease
(NAFLD) are critically needed. This study compared the effects of alternate day fasting (ADF) …

[HTML][HTML] Human hepatic 3D spheroids as a model for steatosis and insulin resistance

M Kozyra, I Johansson, Å Nordling, S Ullah… - Scientific reports, 2018 - nature.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as a public health concern as
reflected in its widespread distribution in the general population. Yet, treatment options are …

Serum selenium and non-alcoholic fatty liver disease (NAFLD) in US adults: National Health and Nutrition Examination Survey (NHANES) 2011–2016

X Wang, YA Seo, SK Park - Environmental Research, 2021 - Elsevier
Background Selenium is an essential trace element that shows beneficial or adverse health
effects depending on the dose. Laboratory studies suggest that high selenium may …

Pediatric obesity: Current concepts

DE Greydanus, M Agana, MK Kamboj, S Shebrain… - Disease-a-Month, 2018 - Elsevier
This discussion reflects on concepts of obesity in children and adolescents in the early 21st
century. It includes reflections on its history, definition, epidemiology, diagnostic …

[HTML][HTML] Adiponectin, leptin, and IGF-1 are useful diagnostic and stratification biomarkers of NAFLD

V Marques, MB Afonso, N Bierig… - Frontiers in …, 2021 - frontiersin.org
Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver
disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to …

[HTML][HTML] From overnutrition to liver injury: AMP-activated protein kinase in nonalcoholic fatty liver diseases

P Zhao, AR Saltiel - Journal of Biological Chemistry, 2020 - ASBMB
Nonalcoholic fatty liver diseases (NAFLDs), especially nonalcoholic steatohepatitis (NASH),
have become a major cause of liver transplant and liver-associated death. However, the …

[HTML][HTML] Insulin-resistance in paediatric age: Its magnitude and implications

M Al-Beltagi, AS Bediwy, NK Saeed - World journal of diabetes, 2022 - ncbi.nlm.nih.gov
Insulin resistance (IR) is insulin failure in normal plasma levels to adequately stimulate
glucose uptake by the peripheral tissues. IR is becoming more common in children and …

The role of microneedle arrays in drug delivery and patient monitoring to prevent diabetes induced fibrosis

E McAlister, M Kirkby, J Dominguez-Robles… - Advanced Drug Delivery …, 2021 - Elsevier
Diabetes affects approximately 450 million adults globally. If not effectively managed,
chronic hyperglycaemia causes tissue damage that can develop into fibrosis. Fibrosis leads …