Benefits and mechanisms of exercise training for knee osteoarthritis

CY Zeng, ZR Zhang, ZM Tang, FZ Hua - Frontiers in physiology, 2021 - frontiersin.org
Knee osteoarthritis is a chronic degenerative disease. Cartilage and subchondral bone
degeneration, as well as synovitis, are the main pathological changes associated with knee …

[HTML][HTML] Mechanical stress abnormalities promote chondrocyte senescence-The pathogenesis of knee osteoarthritis

W Jiang, H Chen, Y Lin, K Cheng, D Zhou… - Biomedicine & …, 2023 - Elsevier
Knee osteoarthritis (KOA) is a common chronic disease in orthopedics, which brings great
pain to patients' life and spirit. Therefore, it is necessary to elucidate the pathogenesis of …

Icariin alleviates osteoarthritis by regulating autophagy of chondrocytes by mediating PI3K/AKT/mTOR signaling

Y Tang, Y Li, D Xin, L Chen, Z Xiong, X Yu - Bioengineered, 2021 - Taylor & Francis
Osteoarthritis (OA) is a chronic degenerative disease that significantly impacts the quality of
life of the elderly population. Recently, the pathogenesis of OA has been reported to involve …

Stromal vascular fraction therapy for knee osteoarthritis: A systematic review

EN Goncharov, OA Koval, E Nikolaevich Bezuglov… - Medicina, 2023 - mdpi.com
Background and Objectives: Knee osteoarthritis (OA) is a widespread joint disease, set to
increase due to aging and rising obesity. Beyond cartilage degeneration, OA involves the …

Stem cells and extrusion 3D printing for hyaline cartilage engineering

O Messaoudi, C Henrionnet, K Bourge, D Loeuille… - Cells, 2020 - mdpi.com
Hyaline cartilage is deficient in self-healing properties. The early treatment of focal cartilage
lesions is a public health challenge to prevent long-term degradation and the occurrence of …

Synovial fluid biomarkers in knee osteoarthritis: a systematic review and quantitative evaluation using BIPEDs criteria

A Boffa, G Merli, L Andriolo, C Lattermann… - Cartilage, 2021 - journals.sagepub.com
Objective The aim of this systematic review was to analyze the evidence about the efficacy of
the several synovial fluid (SF) biomarkers proposed for knee osteoarthritis (OA), categorizing …

Knee osteoarthritis: disease burden, available treatments, and emerging options

M Langworthy, V Dasa… - Therapeutic Advances in …, 2024 - journals.sagepub.com
Osteoarthritis (OA) is a prevalent condition that affects nearly 528 million people worldwide,
including 23% of the global population aged⩾ 40, and is characterized by progressive …

miR-155 inhibits chondrocyte pyroptosis in knee osteoarthritis by targeting SMAD2 and inhibiting the NLRP3/Caspase-1 pathway

G Li, L Xiu, X Li, L Ma, J Zhou - Journal of orthopaedic surgery and …, 2022 - Springer
Objective Knee osteoarthritis (KOA) is based on degenerative pathological changes. miR-
155 is involved in regulating KOA. This study estimated the mechanism of miR-155 in mouse …

Efficacy and safety of corticosteroids, hyaluronic acid, and PRP and combination therapy for knee osteoarthritis: a systematic review and network meta-analysis

X Qiao, L Yan, Y Feng, X Li, K Zhang, Z Lv, C Xu… - BMC Musculoskeletal …, 2023 - Springer
Objective There are many injectable treatments for knee osteoarthritis with different
characteristics and effects, the aim is to understand which one can lead to better and safer …

[HTML][HTML] Mechanisms and applications of the regenerative capacity of platelets-based therapy in knee osteoarthritis

JY Zhang, XN Xiang, X Yu, Y Liu, HY Jiang… - Biomedicine & …, 2024 - Elsevier
Osteoarthritis (OA) is the most prevalent joint disease in the elderly population and its
substantial morbidity and disability impose a heavy economic burden on patients and …