Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases
are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from …

Parkinson's disease is highly heterogeneous in early clinical features and later outcomes.
This makes classifying subgroups of PD relevant to clinical research and practice …

Premotor and nonmotor features of Parkinson's disease : Current Opinion in Neurology
Premotor and nonmotor features of Parkinson's disease : Current Opinion in Neurology Log in or …

Importance We observed a significant correlation between cerebrospinal fluid (CSF) levels
of tau proteins and α-synuclein, but not β-amyloid 1-42 (Aβ1-42), and lower concentration of …

Clinical diagnosis of Parkinson disease (PD) is difficult in early stages of disease, with high
risk of misdiagnosis. The long preclinical phase of PD provides the possibility for early …

Parkinson's disease (PD) is the second commonest neurodegenerative disorder in the world
with a rising prevalence. The pathophysiology is multifactorial but aggregation of misfolded …

Objective We analyzed the longitudinal profile of Alzheimer's disease (AD) cerebrospinal
fluid (CSF) biomarkers in early Parkinson's disease (PD) compared with healthy controls …

Parkinson's disease (PD) is often divided into tremor dominant (TD) and postural instability
gait difficulty (PIGD) subtypes. However, objective measures of gait (eg, stride length …

Reports outlining the association between gait and cognition in Parkinson's disease (PD)
are limited because of methodological issues and a bias toward studying advanced disease …

The blood-brain barrier supplies brain tissues with nutrients and filters certain compounds
from the brain back to the bloodstream. In several neurodegenerative diseases, including …