Recent advances in the label-free characterization of exosomes for cancer liquid biopsy: from scattering and spectroscopy to nanoindentation and nanodevices

R Di Santo, S Romanò, A Mazzini, S Jovanović… - Nanomaterials, 2021 - mdpi.com
Exosomes (EXOs) are nano-sized vesicles secreted by most cell types. They are abundant
in bio-fluids and harbor specific molecular constituents from their parental cells. Due to these …

Antenna-enhanced mid-infrared detection of extracellular vesicles derived from human cancer cell cultures

ME Temperini, F Di Giacinto, S Romanò… - Journal of …, 2022 - Springer
Abstract Background Extracellular Vesicles (EVs) are sub-micrometer lipid-bound particles
released by most cell types. They are considered a promising source of cancer biomarkers …

Sensing red blood cell nano-mechanics: Toward a novel blood biomarker for Alzheimer's disease

M Nardini, G Ciasca, A Lauria, C Rossi… - Frontiers in Aging …, 2022 - frontiersin.org
Red blood cells (RBCs) are characterized by a remarkable elasticity, which allows them to
undergo very large deformation when passing through small vessels and capillaries. This …

Atomic force microscopy in disease‐related studies: Exploring tissue and cell mechanics

S Liu, Y Han, L Kong, G Wang… - Microscopy Research and …, 2024 - Wiley Online Library
Despite significant progress in human medicine, certain diseases remain challenging to
promptly diagnose and treat. Hence, the imperative lies in the development of more …

Machine learning-assisted FTIR analysis of circulating extracellular vesicles for cancer liquid biopsy

R Di Santo, M Vaccaro, S Romanò… - Journal of Personalized …, 2022 - mdpi.com
Extracellular vesicles (EVs) are abundantly released into the systemic circulation, where
they show remarkable stability and harbor molecular constituents that provide biochemical …

[HTML][HTML] Sensing Biomechanical Alterations in Red Blood Cells of Type 1 Diabetes Patients: Potential Markers for Microvascular Complications

R Di Santo, B Niccolini, A Rizzi, L Bertini, DP Marafon… - Biosensors, 2024 - mdpi.com
In physiological conditions, red blood cells (RBCs) demonstrate remarkable deformability,
allowing them to undergo considerable deformation when passing through the …

Elongation index derivative as a potential hemorheological parameter in a diffraction analysis of diabetes mellitus patients' erythrocytes

MD Radmilović, VL Ilić, D Trivanović, A Petakov… - Optical and Quantum …, 2024 - Springer
Comparative analysis of erythrocyte deformability in individuals with Diabetes Mellitus (DM)
and healthy individuals (Control) was represented, focusing on the Elongation index (EI) …