2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of …

SM Grundy, NJ Stone, AL Bailey, C Beam, KK Birtcher… - Circulation, 2019 - Am Heart Assoc
The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B: JACC Focus Seminar 1/4

NS Nurmohamed, AM Navar, JJP Kastelein - Journal of the American …, 2021 - jacc.org
Adding to the foundation of statins, ezetimibe and proprotein convertase subtilisin–kexin
type 9 inhibitors (PCSK9i), novel, emerging low-density lipoprotein cholesterol (LDL-C) …

Bempedoic acid for primary prevention of cardiovascular events in statin-intolerant patients

SE Nissen, V Menon, SJ Nicholls, D Brennan, L Laffin… - Jama, 2023 - jamanetwork.com
Importance The effects of bempedoic acid on cardiovascular outcomes in statin-intolerant
patients without a prior cardiovascular event (primary prevention) have not been fully …

Deep convolutional neural networks to predict cardiovascular risk from computed tomography

R Zeleznik, B Foldyna, P Eslami, J Weiss… - Nature …, 2021 - nature.com
Coronary artery calcium is an accurate predictor of cardiovascular events. While it is visible
on all computed tomography (CT) scans of the chest, this information is not routinely …

High-intensity statin use among patients with atherosclerosis in the US

AJ Nelson, K Haynes, S Shambhu, Z Eapen… - Journal of the American …, 2022 - jacc.org
Background Preventive therapy among patients with established atherosclerotic
cardiovascular disease (ASCVD) is generally underused. Whether new guideline …

Patient‐reported reasons for declining or discontinuing statin therapy: insights from the PALM registry

CK Bradley, TY Wang, S Li, JG Robinson… - Journal of the …, 2019 - Am Heart Assoc
Background Many adults eligible for statin therapy for cardiovascular disease prevention are
untreated. Our objective was to investigate patient‐reported reasons for statin …

Deep learning to assess long-term mortality from chest radiographs

MT Lu, A Ivanov, T Mayrhofer, A Hosny… - JAMA network …, 2019 - jamanetwork.com
Importance Chest radiography is the most common diagnostic imaging test in medicine and
may also provide information about longevity and prognosis. Objective To develop and test …

[HTML][HTML] Statins utilization trends and expenditures in the US before and after the implementation of the 2013 ACC/AHA guidelines

A Matyori, CP Brown, A Ali, F Sherbeny - Saudi Pharmaceutical Journal, 2023 - Elsevier
Importance Statins are drugs of choice in treating hyperlipidemia and preventing or reducing
cardiovascular diseases. Purpose Explore statins utilization and expenditure trends in the …

Gaps in guideline-based lipid-lowering therapy for secondary prevention in the United States: a retrospective cohort study of 322 153 patients

AM Navar, AA Kolkailah, A Gupta… - … Quality and Outcomes, 2023 - Am Heart Assoc
BACKGROUND: Many patients with atherosclerotic cardiovascular disease (ASCVD) are not
on guideline-recommended statin therapy. We evaluated utilization of statins and other lipid …

[HTML][HTML] Therapeutic inertia in cardiovascular disease prevention: time to move the bar

DL Dixon, G Sharma, PB Sandesara, E Yang… - Journal of the American …, 2019 - jacc.org
The decline in cardiovascular (CV) mortality over the last 50 years can be largely attributed
to advances in preventive care (1). Despite these improvements, atherosclerotic …