Droplet microfluidics for the construction of compartmentalised model membranes

T Trantidou, MS Friddin, A Salehi-Reyhani, O Ces… - Lab on a Chip, 2018 - pubs.rsc.org
The design of membrane-based constructs with multiple compartments is of increasing
importance given their potential applications as microreactors, as artificial cells in synthetic …

Functional aqueous droplet networks

MJ Booth, VR Schild, FG Downs, H Bayley - Molecular BioSystems, 2017 - pubs.rsc.org
Droplet interface bilayers (DIBs), comprising individual lipid bilayers between pairs of
aqueous droplets in an oil, are proving to be a useful tool for studying membrane proteins …

Multi-responsive hydrogel structures from patterned droplet networks

FG Downs, DJ Lunn, MJ Booth, JB Sauer… - Nature …, 2020 - nature.com
Responsive hydrogels that undergo controlled shape changes in response to a range of
stimuli are of interest for microscale soft robotic and biomedical devices. However, these …

Parallel transmission in a synthetic nerve

CEG Hoskin, VR Schild, J Vinals, H Bayley - Nature Chemistry, 2022 - nature.com
Bioelectronic devices that are tetherless and soft are promising developments in medicine,
robotics and chemical computing. Here, we describe bioinspired synthetic neurons …

Controlled packing and single-droplet resolution of 3D-printed functional synthetic tissues

A Alcinesio, OJ Meacock, RG Allan, C Monico… - Nature …, 2020 - nature.com
Abstract 3D-printing networks of droplets connected by interface bilayers are a powerful
platform to build synthetic tissues in which functionality relies on precisely ordered …

Light-patterning of synthetic tissues with single droplet resolution

MJ Booth, V Restrepo Schild, SJ Box, H Bayley - Scientific reports, 2017 - nature.com
Synthetic tissues can be generated by forming networks of aqueous droplets in lipid-
containing oil. Each droplet contains a cell-free expression system and is connected to its …

Challenges and opportunities in achieving the full potential of droplet interface bilayers

EB Stephenson, JL Korner, KS Elvira - Nature Chemistry, 2022 - nature.com
Abstract Model membranes can be used to elucidate the intricacies of the chemical
processes that occur in cell membranes, but the perfectly biomimetic, yet bespoke, model …

Synthetic tissues

H Bayley, I Cazimoglu… - Emerging Topics in Life …, 2019 - portlandpress.com
While significant advances have been achieved with non-living synthetic cells built from the
bottom-up, less progress has been made with the fabrication of synthetic tissues built from …

Highly Resistive Biomembranes Coupled to Organic Transistors enable Ion‐Channel Mediated Neuromorphic Synapses

JJ Maraj, EA Schafer, MM Mansour… - Advanced Electronic …, 2024 - Wiley Online Library
Organic electrochemical transistors (OECTs) functionalized with lipid membranes could
enable new hybrid synapses for sensing and neuromorphic computing in biological media …

Droplet-based membranous soft materials

MM Makhoul-Mansour, EC Freeman - Langmuir, 2021 - ACS Publications
Inspired by the structure and functionality of natural cellular tissues, droplet interface bilayer
(DIB)-based materials strategically combine model membrane assembly techniques and …