Introduction. One in eight of all total hip replacements requires revision within 10 years, 60%
because of wear-related complications. The bearing surfaces may be made of …

The metal/metal alloy-based implants and prostheses are in use for over a century, and the
rejections, revisions, and metal particle-based toxicities were reported concurrently …

Background: Dilated cardiomyopathy is a frequent disease responsible for 40–50% of cases
of heart failure. Idiopathic cardiomyopathy is a primary disorder often related to …

Objective To review and summarize biomarker data published from April 2014 to May 2015
to provide insight to the ongoing work in the field of osteoarthritis (OA). Furthermore, to …

Cobalt can cause a distinctive, rapidly progressive and reversible depression of cardiac
systolic function, which is readily distinguished from other causes of cardiomyopathy …

Introduction The incidence and natural course of pseudotumors in metal-on-metal total hip
arthroplasties is largely unknown. The objective of this study was to identify the true …

Introduction. There has been some recent concern regarding possible systemic health
effects resulting from elevated blood cobalt concentrations in patients with cobalt containing …

Elevated levels of circulating cobalt ions have been linked with a wide range of systemic
complications including neurological, endocrine, and cardiovascular symptoms. Case …

Cobalt (Co) can stimulate erythropoietin production in individuals at doses exceeding 25 mg
CoCl2/day. Co has also been shown to exert effects on the thyroid gland, heart and nervous …

Introduction Cobalt is a mitochondrial toxin, clinical cobaltism manifests with constitutional,
neurologic, and cardiovascular symptomatology. Cobalt's severe toxidrome is known …