The role of MicroRNAs in breast cancer and the challenges of their clinical application

JP Muñoz, P Pérez-Moreno, Y Pérez, GM Calaf - Diagnostics, 2023 - mdpi.com
MicroRNAs (miRNAs) constitute a subclass of non-coding RNAs that exert substantial
influence on gene-expression regulation. Their tightly controlled expression plays a pivotal …

Review on the role of salivary biomarkers in the diagnosis of mild traumatic brain injury and post-concussion syndrome

I Mavroudis, F Petridis, IM Balmus, A Ciobica… - Diagnostics, 2023 - mdpi.com
(1) Background: While mild traumatic brain injuries (TBIs) are a major public health issue,
post-concussion syndrome (PCS) remains a controversial entity. In both cases, the clinical …

Spitting in the wind?—The challenges of RNA sequencing for biomarker discovery from saliva

A Gosch, R Banemann, G Dørum, C Haas… - International journal of …, 2024 - Springer
Forensic trace contextualization, ie, assessing information beyond who deposited a
biological stain, has become an issue of great and steadily growing importance in forensic …

Exosomal miRNAs as Biomarkers of Ischemic Stroke

AM Ciaccio, A Tuttolomondo - Brain Sciences, 2023 - mdpi.com
Exosomes are small lipid bilayer membrane particles released from all living cells into the
extracellular environment. They carry several molecules and have a critical role in cell–cell …

Obtaining miRNA from saliva—comparison of sampling and purification methods

A Urbizu, L Arnaldo, K Beyer - International Journal of Molecular Sciences, 2023 - mdpi.com
The use of saliva as a biomarker source has advantages over other biofluids and imaging
techniques, and miRNAs are ideal biomarker candidates. They are involved in numerous …

[HTML][HTML] Influence of analytical procedures on miRNA expression analyses in saliva samples

MJJ Scheurer, A Wagner, A Sakkas, S Pietzka… - Journal of Cranio …, 2024 - Elsevier
Aim of this study was to demonstrate the influence of different analytical procedures and
techniques on the resulting miRNA expression profile in healthy control subjects and tumor …

[HTML][HTML] Preliminary Evidence for Neuronal Dysfunction Following Adverse Childhood Experiences: An Investigation of Salivary MicroRNA Within a High-Risk Youth …

AT Schmidt, SD Hicks, BK Bergquist, KA Maloney… - Genes, 2024 - mdpi.com
Background/Objectives: Adverse childhood experiences (ACEs) are potent drivers of
psychopathology and neurological disorders, especially within minoritized populations …

[HTML][HTML] A Pilot Study of Saliva MicroRNA Signatures in Children with Moderate-to-Severe Traumatic Brain Injury

R Ciancaglini, AS Botash, V Armijo-Garcia… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Traumatic brain injury (TBI) is a leading cause of death and
disability in children. Currently, no biological test can predict outcomes in pediatric TBI …

The presence of ACE2 and regulatory miRNAs (miR-200c-3p and miR-421-5p) in the saliva of periodontitis patients post-COVID-19 vaccination

BM Bachtiar, N Haerani, Y Soeroso, N Ismah… - Frontiers in Dental …, 2024 - frontiersin.org
The effectiveness of COVID-19 mRNA vaccines in individuals with periodontitis is crucial.
This study evaluated the efficacy of the BNT162b2 vaccine in individuals with periodontitis …

[HTML][HTML] Stability of circulating miRNA in saliva: The influence of sample associated pre-analytical variables

C Romani, M Baronchelli, C Assoni, D Mattavelli… - Clinica Chimica …, 2024 - Elsevier
Background and aims Increasing evidence supports the practicability of salivary cell-free (cf)
miRNA as liquid biopsy markers in cancers. Its successful translation in the clinical setting …