Skin is attractive for drug therapy because it offers an easily accessible route without first-
pass metabolism. Transdermal drug delivery is also associated with high patient compliance …

Ceramides are essential constituents of the skin barrier that allow humans to live on dry
land. Reduced levels of ceramides have been associated with skin diseases, eg, atopic …

Surface-active amphiphiles find applications in a wide range of areas of industry such as
agrochemicals, personal care, and pharmaceuticals. In many of these applications …

Surface-active compounds present in aerosols can increase their cloud condensation nuclei
(CCN) activation efficiency by reducing the surface tension (σ) in the growing droplets …

Oleic acid and oleyl alcohol are commonly used permeation and penetration enhancers to
facilitate topical drug delivery. Here, we aimed to better understand the mechanism of their …

Ceramides are known to be a key component of the stratum corneum, the outermost
protective layer of the skin that controls barrier function. In this work, molecular dynamics …

Cell membrane fatty acids influence fundamental properties of the plasma membrane,
including membrane fluidity, protein functionality, and lipid raft signalling. Evidence suggests …

Transdermal drug delivery is a passive diffusion process of an active compound through the
skin which is affected by drug solubility in the multilamellar lipidic matrix of the stratum …

Nanoplastics are mainly generated from the decomposition of plastic waste and artificial
production and have attracted much attention due to their wide distribution in the …

The structure of the stratum corneum (SC) and the corresponding skin barrier develops from
before birth up to about 4 years of age. Large subject-to-subject variability within an age …