Peroxynitrite is a short-lived and reactive biological oxidant formed from the diffusion-
controlled reaction of the free radicals superoxide (O2•–) and nitric oxide (• NO). In this …

Oxidative stress is a common mediator in pathogenicity of established cardiovascular risk
factors. Furthermore, it likely mediates effects of emerging, less well-defined variables that …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Free radicals and other reactive oxygen species (ROS) are constantly formed in the human
body. Free‐radical mechanisms have been implicated in the pathology of several human …

This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

Markers of oxidative stress are increased in chronic obstructive pulmonary disease (COPD)
and reactive oxygen species (ROS) are able to alter biological molecules, signaling …

The topic of free radicals and antioxidants is widely dis—cussed, not only in the biologic and
medical literature but also in reading for the general public. Advertisements urge you to …

Atherosclerosis is a cardiovascular disease (CVD) known widely world wide. Several
hypothesizes are suggested to be involved in the narrowing of arteries during process of …

Superoxide (O2-.), nitric oxide (. NO), and their reaction product peroxynitrite (ONOO-) have
all been shown to independently exert toxic target molecule reactions. Because these …

This article reviews our current understanding of the mechanisms of low-density lipoprotein
(LDL) oxidation and the potential role of oxidized lipoproteins in atherosclerosis. Studies in …