The Diversity of Escherichia coli Pathotypes and Vaccination Strategies against This Versatile Bacterial Pathogen

P Pokharel, S Dhakal, CM Dozois - Microorganisms, 2023 - mdpi.com
Escherichia coli (E. coli) is a gram-negative bacillus and resident of the normal intestinal
microbiota. However, some E. coli strains can cause diseases in humans, other mammals …

Development of a low-cost paper-based ELISA method for rapid Escherichia coli O157: H7 detection

B Pang, C Zhao, L Li, X Song, K Xu, J Wang, Y Liu… - Analytical …, 2018 - Elsevier
Abstract Escherichia coli O157: H7 (E. coli O157: H7) has become one of the most
dangerous foodborne pathogenic bacteria around the world. Currently, because of the …

Intestinal Pathogenic Escherichia coli: Insights for Vaccine Development

M Rojas-Lopez, R Monterio, M Pizza… - Frontiers in …, 2018 - frontiersin.org
Diarrheal diseases are one of the major causes of mortality among children under five years
old and intestinal pathogenic Escherichia coli (InPEC) plays a role as one of the large …

Development of a gold nanoparticle vaccine against enterohemorrhagic Escherichia coli O157: H7

JI Sanchez-Villamil, D Tapia, AG Torres - MBio, 2019 - Am Soc Microbiol
Here we exploit the natural properties of a synthetic nanoparticle (NP) scaffold as a subunit
vaccine against enterohemorrhagic Escherichia coli (EHEC). Two EHEC-specific …

Efficacy of EHEC gold nanoparticle vaccines evaluated with the Shiga toxin-producing Citrobacter rodentium mouse model

S Bowser, A Melton-Celsa… - Microbiology …, 2024 - Am Soc Microbiol
Enterohemorrhagic Escherichia coli (EHEC) is a group of pathogenic bacteria responsible
for several foodborne-associated outbreaks of human diarrheal disease. Although EHEC is …

Rapid and Ultrasensitive Colorimetric Biosensors for Onsite Detection of Escherichia coli O157:H7 in Fluids

B Pan, AY El-Moghazy, M Norwood, N Nitin, G Sun - ACS sensors, 2024 - ACS Publications
This study presents a breakthrough in the field of onsite bacterial detection, offering an
innovative, rapid, and ultrasensitive colorimetric biosensor for the detection of Escherichia …

Optimization of Multivalent Gold Nanoparticle Vaccines Eliciting Humoral and Cellular Immunity in an In Vivo Model of Enterohemorrhagic Escherichia coli O157:H7 …

JI Sanchez-Villamil, D Tapia, AG Torres - Msphere, 2022 - Am Soc Microbiol
ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) O157: H7 remains a pathogen of
significance and high consequence around the world. This outcome is due in part to the high …

Oral Administration with Live Attenuated Citrobacter rodentium Protects Immunocompromised Mice from Lethal Infection

S Wang, X Xia, Y Liu, F Wan - Infection and immunity, 2022 - Am Soc Microbiol
Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are
important causative agents for foodborne diseases worldwide. Besides antibiotic treatment …

Further Evaluation of Enterohemorrhagic Escherichia coli Gold Nanoparticle Vaccines Utilizing Citrobacter rodentium as the Model Organism

S Bowser, A Melton-Celsa, I Chapartegui-González… - Vaccines, 2024 - mdpi.com
Enterohemorrhagic E. coli (EHEC) is a group of pathogenic bacteria that is associated with
worldwide human foodborne diarrheal illnesses and the development of hemolytic uremic …

A new candidate epitope-based vaccine against PspA PhtD of Streptococcus pneumoniae: a computational experimental approach

M Shafaghi, Z Bahadori, SM Barzi, E Afshari… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction Pneumococcus is an important respiratory pathogen that is associated with high
rates of death in newborn children and the elderly. Given the disadvantages of current …