Covering: up to October 2023Many bioactive natural products are synthesized by
microorganisms that are either difficult or impossible to cultivate under laboratory conditions …

In this study, the genomic tools were used to characterize the probiotic and bactericidal
potential of Lactiplantibacillus plantarum HY41. Firstly, the strain was found to carry two …

Lanthipeptides make up a large group of natural products that belong to the ribosomally
synthesized and post-translationally modified peptides (RiPPs). Lanthipeptides contain …

Modification of the N-and C-termini of peptides enhances their stability against degradation
by exopeptidases. The biosynthetic pathways of many peptidic natural products feature …

Lanthipeptides are a large group of ribosomally encoded peptides cyclized by thioether and
methylene bridges, which include the lantibiotics, lanthipeptides with antimicrobial activity …

Cyclic peptides, with remarkable stability, cellular permeability, and proteolysis resistance,
display promising potential in pharmaceutical applications. Labionin (Lab), a unique bicyclic …

The increasing prevalence of drug-resistant bacteria has prompted the search for alternative
approaches to address bacterial infections. Lanthipeptides, which are small molecule …

Harnessing Microbial Peptides for Drug Discovery offers a concise introduction for
researchers new to antimicrobial peptides. This primer provides essential information to …

Environmental concerns are increasingly fueling interest in engineered living materials
derived from microbial sources. Melanin biosynthesis in microbes, particularly facilitated by …

Natural products have served various functions in human civilization for thousands of years.
From food stuffs like caffeine to pharmaceuticals such as penicillin or vancomycin, they are …