Current state of the art MRI for the longitudinal assessment of cystic fibrosis

JC Woods, JM Wild, MO Wielpütz… - Journal of Magnetic …, 2020 - Wiley Online Library
Pulmonary MRI can now provide high‐resolution images that are sensitive to early disease
and specific to inflammation in cystic fibrosis (CF) lung disease. With specificity and function …

Lung MRI with hyperpolarised gases: current & future clinical perspectives

NJ Stewart, LJ Smith, HF Chan… - The British Journal of …, 2022 - academic.oup.com
The use of pulmonary MRI in a clinical setting has historically been limited. Whilst CT
remains the gold-standard for structural lung imaging in many clinical indications, technical …

Expanding applications of pulmonary MRI in the clinical evaluation of lung disorders: Fleischner Society position paper

H Hatabu, Y Ohno, WB Gefter, G Parraga, B Madore… - Radiology, 2020 - pubs.rsna.org
Pulmonary MRI provides structural and quantitative functional images of the lungs without
ionizing radiation, but it has had limited clinical use due to low signal intensity from the lung …

Time to get serious about the detection and monitoring of early lung disease in cystic fibrosis

KJ Bayfield, TA Douglas, T Rosenow, JC Davies… - Thorax, 2021 - thorax.bmj.com
Structural and functional defects within the lungs of children with cystic fibrosis (CF) are
detectable soon after birth and progress throughout preschool years often without overt …

[HTML][HTML] Multicentre standardisation of chest MRI as radiation-free outcome measure of lung disease in young children with cystic fibrosis

MO Wielpütz, O von Stackelberg, M Stahl… - Journal of Cystic …, 2018 - Elsevier
Background A recent single-centre study demonstrated that MRI is sensitive to detect early
abnormalities in the lung and response to therapy in infants and preschool children with …

129Xe and Free‐Breathing 1H Ventilation MRI in Patients With Cystic Fibrosis: A Dual‐Center Study

H Marshall, A Voskrebenzev, LJ Smith… - Journal of Magnetic …, 2023 - Wiley Online Library
Background Free‐breathing 1H ventilation MRI shows promise but only single‐center
validation has yet been performed against methods which directly image lung ventilation in …

Hyperpolarized gas magnetic resonance imaging of pediatric cystic fibrosis lung disease

G Santyr, N Kanhere, F Morgado, JH Rayment… - Academic radiology, 2019 - Elsevier
Conventional pulmonary function tests appear normal in early cystic fibrosis (CF) lung
disease. Therefore, new diagnostic approaches are required that can detect CF lung …

19F MRI of the Lungs Using Inert Fluorinated Gases: Challenges and New Developments

MJ Couch, IK Ball, T Li, MS Fox… - Journal of Magnetic …, 2019 - Wiley Online Library
Fluorine‐19 (19F) MRI using inhaled inert fluorinated gases is an emerging technique that
can provide functional images of the lungs. Inert fluorinated gases are nontoxic, abundant …

Hyperpolarized gas MRI in pulmonology

AL Kern, J Vogel-Claussen - The British journal of radiology, 2018 - academic.oup.com
Lung diseases have a high prevalence amongst the world population and their early
diagnosis has been pointed out to be key for successful treatment. However, there is still a …

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements

M Sharma, PV Wyszkiewicz… - Physics in Medicine …, 2022 - iopscience.iop.org
Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …