Autophagosome formation requires sequential translocation of autophagy-specific proteins
to membranes enriched in PI3P and connected to the ER. Preceding this, the earliest …

Autophagy is a cytosolic degradative pathway, which through a series of complicated
membrane rearrangements leads to the formation of a unique double membrane vesicle, the …

Autophagy is a highly dynamic intracellular process involving interactions between protein
complexes and membranes. Direct observation of these components in living cells provides …

Containment and clearance of invading pathogens, such as viruses, by suppression of viral
replication through antiviral mechanisms (eg CRISPR, interferon response or programmed …

DNA guanine quadruplexes (G4s) are non-canonical structures formed through self-
recognition of four guanines into stacked tetrads. G4s are highly prevalent at regulatory …