Virus-like particle vaccinology, from bench to bedside
MO Mohsen, MF Bachmann - Cellular & molecular immunology, 2022 - nature.com
Virus-like particles (VLPs) have become key tools in biology, medicine and even
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …
engineering. After their initial use to resolve viral structures at the atomic level, VLPs were …
Interaction between virus-like particles (VLPs) and pattern recognition receptors (PRRs) from dendritic cells (DCs): toward better engineering of VLPs
J Zepeda-Cervantes, JO Ramírez-Jarquín… - Frontiers in …, 2020 - frontiersin.org
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs).
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
DCs are the most potent antigen presenting cells (APCs) and their activation prompts the …
Past, present, and future of allergen immunotherapy vaccines
Y Dorofeeva, I Shilovskiy, I Tulaeva, M Focke‐Tejkl… - Allergy, 2021 - Wiley Online Library
Allergen‐specific immunotherapy (AIT) is an allergen‐specific form of treatment for patients
suffering from immunoglobulin E (IgE)‐associated allergy; the most common and important …
suffering from immunoglobulin E (IgE)‐associated allergy; the most common and important …
New routes and opportunities for modular construction of particulate vaccines: stick, click, and glue
Vaccines based on virus-like particles (VLPs) can induce potent B cell responses. Some non-
chimeric VLP-based vaccines are highly successful licensed products (eg, hepatitis B …
chimeric VLP-based vaccines are highly successful licensed products (eg, hepatitis B …
Vaccine against peanut allergy based on engineered virus-like particles displaying single major peanut allergens
Background Peanut allergy is a severe and increasingly frequent disease with high medical,
psychosocial, and economic burden for affected patients and wider society. A causal, safe …
psychosocial, and economic burden for affected patients and wider society. A causal, safe …
The 3Ds in virus‐like particle based‐vaccines: “Design, Delivery and Dynamics”
MO Mohsen, G Augusto… - Immunological reviews, 2020 - Wiley Online Library
Vaccines need to be rationally designed in order be delivered to the immune system for
maximizing induction of dynamic immune responses. Virus‐like particles (VLPs) are ideal …
maximizing induction of dynamic immune responses. Virus‐like particles (VLPs) are ideal …
Perspectives in allergen immunotherapy: 2019 and beyond
The seventh “Future of the Allergists and Specific Immunotherapy (FASIT)” workshop held in
2019 provided a platform for global experts from academia, allergy clinics, regulatory …
2019 provided a platform for global experts from academia, allergy clinics, regulatory …
The next generation virus‐like particle platform for the treatment of peanut allergy
Background Allergy to peanut is one of the leading causes of anaphylactic reactions among
food allergic patients. Immunization against peanut allergy with a safe and protective …
food allergic patients. Immunization against peanut allergy with a safe and protective …
State‐of‐the‐art in marketed adjuvants and formulations in allergen immunotherapy: a position paper of the European Academy of Allergy and Clinical Immunology …
Since the introduction of allergen immunotherapy (AIT) over 100 years ago, focus has been
on standardization of allergen extracts, with reliable molecular composition of allergens …
on standardization of allergen extracts, with reliable molecular composition of allergens …
[HTML][HTML] Immunization of cats to induce neutralizing antibodies against Fel d 1, the major feline allergen in human subjects
F Thoms, GT Jennings, M Maudrich, M Vogel… - Journal of Allergy and …, 2019 - Elsevier
Background Cat allergy in human subjects is usually caused by the major cat allergen Fel d
1 and is found in approximately 10% of the Western population. Currently, there is no …
1 and is found in approximately 10% of the Western population. Currently, there is no …