Mass spectrometry–based quantitative proteomics is a powerful tool for gaining insights into
function and dynamics of biological systems. However, peptides with different sequences …

The cyclin-dependent kinases (Cdks) regulate many cellular processes, including the cell
cycle, neuronal development, transcription, and posttranscriptional processing. To perform …

This review retraces the role of stable isotopes and mass spectrometry in the life sciences.
The timeline is divided into four segments covering the years 1920–1950, 1950–1980, 1980 …

CDK9 is a prominent member of the transcriptional CDKs subfamily, a group of kinases
whose function is to control the primary steps of mRNA synthesis and processing by …

In recent years, quantitative proteomic research attracts great attention because of the
urgent needs in biological and clinical research, such as biomarker discovery and …

Cow's milk allergy is the most common food allergy, and caseins are the major allergens in
milk. A quantitative proteomics method based on liquid chromatography coupled to mass …

We utilized a setup based on extensive pre‐fractionation of proteolytic peptides and
nanoflow reversed‐phase LC‐MS/MS to identify the (sub) proteome of human follicular fluid …

Positive transcription elongation factor b (P‐TEFb), which comprises cyclin‐dependent
kinase 9 (CDK9) kinase and cyclin T subunits, is an essential kinase complex in human …

Label‐based quantitative mass spectrometry analysis of affinity purified complexes, with its
built‐in negative controls and relative ease of use, is an increasingly popular choice for …

Inducible transcriptional elongation is a rapid, stereotypic mechanism for activating
immediate early immune defense genes by the epithelium in response to viral pathogens …