Hippocampal dosimetry correlates with the change in neurocognitive function after hippocampal sparing during whole brain radiotherapy: a prospective study

PF Tsai, CC Yang, CC Chuang, TY Huang, YM Wu… - Radiation …, 2015 - Springer
Background Whole brain radiotherapy (WBRT) has been the treatment of choice for patients
with brain metastases. However, change/decline of neurocognitive functions (NCFs) …

[HTML][HTML] Comparison of conventional and hippocampus-sparing radiotherapy in nasopharyngeal carcinoma: In silico study and systematic review

M Peternel, A Jenko, P Peterlin, L Petrovič… - Clinical and …, 2024 - Elsevier
Background and purpose Radiation-induced damage to the hippocampi can cause
cognitive decline. International recommendations for nasopharyngeal cancer (NPC) …

[HTML][HTML] Radiation-induced gray matter atrophy in patients with nasopharyngeal carcinoma after intensity modulated radiotherapy: a MRI magnetic resonance imaging …

L Shi, FL Du, ZW Sun, L Zhang, YY Chen… - … Imaging in Medicine …, 2018 - ncbi.nlm.nih.gov
Background Gray matter (GM) damage after radiotherapy (RT) in nasopharyngeal
carcinoma (NPC) patients can result in cognitive impairment, while there may be no visible …

Neurological complications of modern radiotherapy for head and neck cancer

JCH Chow, JCS Ho, KM Cheung, D Johnson… - Radiotherapy and …, 2024 - Elsevier
Radiotherapy is one of the mainstay treatment modalities for the management of non-
metastatic head and neck cancer (HNC). Notable improvements in treatment outcomes have …

Measuring out-of-field dose to the hippocampus in common radiotherapy indications

H Auerbach, Y Dzierma, M Schürmann, C Rübe… - Radiation …, 2023 - Springer
Background The high susceptibility of the hippocampus region to radiation injury is likely the
causal factor of neurocognitive dysfunctions after exposure to ionizing radiation. Repetitive …

Automatic segmentation of hippocampus in hippocampal sparing whole brain radiotherapy: A multitask edge‐aware learning

Q Qiu, Z Yang, S Wu, D Qian, J Wei, G Gong… - Medical …, 2021 - Wiley Online Library
Purpose This study aimed to improve the accuracy of the hippocampus segmentation
through multitask edge‐aware learning. Method We developed a multitask framework for …

[HTML][HTML] Multi-domain neurocognitive impairment following definitive intensity-modulated radiotherapy for nasopharyngeal cancer: a cross-sectional study

JCH Chow, J Lee, MMP Lai, S Li, AMC Lau… - Radiotherapy and …, 2024 - Elsevier
Introduction Neurocognitive impairment from inadvertent brain irradiation is common
following intensity-modulated radiotherapy (IMRT) for nasopharyngeal carcinoma (NPC) …

Prognosis of hippocampal function after sub-lethal irradiation brain injury in patients with nasopharyngeal carcinoma

SCJ Chen, Y Abe, PT Fang, YJ Hsieh, YI Yang, TY Lu… - Scientific reports, 2017 - nature.com
This work emphasizes the value of assessing hippocampal function by making a timely MRI-
based prognosis following a minor dose of hippocampal irradiation after nasopharyngeal …

Results of the radiation dose of head, body and tail of hippocampus in nasopharyngeal carcinoma patients treated with intensity modulated radiotherapy

S Zong-Wen, S Lei, L Qinglin, K Yue, D Feng-Lei… - Scientific reports, 2018 - nature.com
This study is to analyze the radiation dose of head, body and tail of hippocampus (HC) of
nasopharyngeal carcinoma (NPC) patients treated with intensity modulated radiotherapy …

[HTML][HTML] Dosimetric Evaluation of Hippocampus Sparing Intensity Modulated Radiation Therapy in Patients With Stage T1-T2 and Stage T3-T4 Nasopharyngeal …

X Zhou, K Wu, N Prasad, S Jaiswal, B Jiang, X Li… - Advances in Radiation …, 2024 - Elsevier
Purpose To compare the hippocampus (HPC) dose reduced by HPC-sparing intensity
modulated radiation therapy (IMRT) plans between nasopharyngeal carcinoma (NPC) …