Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to
brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged …

Abstract Purpose of Review Delayed cerebral ischemia (DCI) is common after subarachnoid
hemorrhage (SAH) and represents a significant cause of poor functional outcome. DCI was …

Mounting evidence has suggested that modulating microglia polarization from pro-
inflammatory M1 phenotype to anti-inflammatory M2 state might be a potential therapeutic …

Aneurysmal subarachnoid hemorrhage (SAH) can lead to devastating outcomes including
vasospasm, cognitive decline, and even death. Currently, treatment options are limited for …

Subarachnoid hemorrhage (SAH) has a high mortality rate and causes long-term disability
in many patients, often associated with cognitive impairment. However, the pathogenesis of …

Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating disease, which mainly
caused by the rupture of an intracranial aneurysm. Clinical trials have demonstrated that …

Aneurysmal subarachnoid hemorrhage has a high mortality rate and, for those who survive
this devastating injury, can lead to lifelong impairment. Clinical trials have demonstrated that …

Rodents are the most widely used experimental animals in stroke research due to their
similar vascular anatomy, high reproductive rates, and availability of transgenic models …

Microglia are the principal resident immune cells in the central nervous system (CNS) and
play important roles in the development of CNS disorders. In recent years, there have been …

Aneurysmal subarachnoid hemorrhage (SAH) is a devastating disease that leads to poor
neurological outcomes and is characterized by both vascular and neural pathologies …