Replication of plasmid deoxyribonucleic acid (DNA) is dependent on three stages: initiation,
elongation, and termination. The first stage, initiation, depends on plasmid-encoded …

A general scheme of λ phage and plasmid DNA replication in Escherichia coli is presented,
and results of in vivo experiments from the authors' laboratory are superimposed. The …

We examined the role of two Escherichia coli heat shock proteins, the dnaK and dnaJ gene
products, during the initiation of lambda dv DNA replication in vitro. Using 14C-labeled …

The complex formed between the dnaB and dnaC replication proteins of Escherichia coli is
stabilized by ATP binding to dnaC. The dnaB 6-dnaC 6-ATP 6 complex can be maintained …

Summary An AAA+ ATPase, DnaC, delivers DnaB helicase at the E. coli chromosomal origin
by a poorly understood process. This report shows that mutant proteins bearing alanine …

The bacteriophage lambda P protein promoters replication of the phage chromosome by
recruiting a key component of the cellular replication machinery to the viral origin …

Proteins that bind and hydrolyze ATP are frequently involved in the early steps of DNA
replication. Recent studies of Saccharomyces cerevisiae suggest that two members of the …

Abstract Background: The hexameric helicase DnaB unwinds the DNA duplex at the
Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both …

Spatial organization of biological processes allows for variability in molecular outcomes and
coordinated development. Here, we investigate how organization underpins phage lambda …

Binding of the O protein of phage λ to the replication origin (oriλ) results in the formation of
an organized nucleoprotein structure termed the O-some. The O-some serves to localize …