Chitosan derivatives and their application in biomedicine

W Wang, Q Meng, Q Li, J Liu, M Zhou, Z Jin… - International journal of …, 2020 - mdpi.com
Chitosan is a product of the deacetylation of chitin, which is widely found in nature. Chitosan
is insoluble in water and most organic solvents, which seriously limits both its application …

Stimuli-responsive polymeric nanovaccines toward next-generation immunotherapy

L Mao, P Ma, X Luo, H Cheng, Z Wang, E Ye, XJ Loh… - ACS …, 2023 - ACS Publications
The development of nanovaccines that employ polymeric delivery carriers has garnered
substantial interest in therapeutic treatment of cancer and a variety of infectious diseases …

Toll-like receptor (TLRs) agonists and antagonists for COVID-19 treatments

ZM Liu, MH Yang, K Yu, ZX Lian… - Frontiers in Pharmacology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) rapidly infects
humans and animals which make coronavirus disease 2019 (COVID-19) a grievous …

Ionotropic gelation of chitosan flat structures and potential applications

P Sacco, S Pedroso-Santana, Y Kumar, N Joly… - Molecules, 2021 - mdpi.com
The capability of some polymers, such as chitosan, to form low cost gels under mild
conditions is of great application interest. Ionotropic gelation of chitosan has been used …

An overview of recent insights into the response of TLR to SARS-CoV-2 infection and the potential of TLR agonists as SARS-CoV-2 vaccine adjuvants

MEH Kayesh, M Kohara, K Tsukiyama-Kohara - Viruses, 2021 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led
to coronavirus disease (COVID-19), a global health pandemic causing millions of deaths …

Eosinophils and COVID-19: diagnosis, prognosis, and vaccination strategies

HF Rosenberg, PS Foster - Seminars in immunopathology, 2021 - Springer
The unprecedented impact of the coronavirus disease 2019 (COVID-19) pandemic has
resulted in global challenges to our health-care systems and our economic security. As …

Polymer nanoparticles as adjuvants in cancer immunotherapy

S Li, X Feng, J Wang, L He, C Wang, J Ding, X Chen - Nano Research, 2018 - Springer
Immunotherapy is a promising strategy to inhibit cancer progression via activation of the
immune system. In immunotherapy, adjuvants as immunologic stimulants or delivery …

Inulin and its application in drug delivery

F Afinjuomo, S Abdella, SH Youssef, Y Song, S Garg - Pharmaceuticals, 2021 - mdpi.com
Inulin's unique and flexible structure, stabilization/protective effects, and organ targeting
ability make it an excellent drug delivery carrier compared to other biodegradable …

Polymeric nanoparticle-based vaccine adjuvants and delivery vehicles

EA Grego, AC Siddoway, M Uz, L Liu… - … for Rational Vaccine …, 2020 - Springer
As vaccine formulations have progressed from including live or attenuated strains of
pathogenic components for enhanced safety, developing new adjuvants to more effectively …

Site-directed non-covalent polymer-drug complexes for inflammatory bowel disease (IBD): formulation development, characterization and pharmacological evaluation

SS Kesharwani, R Ahmad, MA Bakkari… - Journal of Controlled …, 2018 - Elsevier
Abstract Inflammatory Bowel Diseases (IBD) is a debilitating condition that affects~ 70,000
new people every year and has been described as “an expensive disease with no known …