The present article discusses the role of light in altering autophagy, both within the outer
retina (retinal pigment epithelium, RPE, and the outer segment of photoreceptors) and the …

The seminal role of autophagy during age-related macular degeneration (AMD) lies in the
clearance of a number of reactive oxidative species that generate dysfunctional …

Light is necessary for life, but prolonged exposure to artificial light is a matter of increasing
health concern. Humans are exposed to increased amounts of light in the blue spectrum …

PERK is an endoplasmic reticulum (ER) transmembrane sensor that phosphorylates eIF2α
to initiate the Unfolded Protein Response (UPR). eIF2α phosphorylation promotes stress …

Light discrimination according to colour can confer survival advantages by guiding animals
towards food and shelter and away from potentially harmful situations,. Such colour …

Potent neuroprotective effects of photobiomodulation with 670 nm red light (RL) have been
demonstrated in several models of retinal disease. RL improves mitochondrial metabolism …

Lentinula edodes (shiitake mushroom) is one of the most important edible mushrooms
worldwide. The L. edodes cultivation cycle includes a unique developing stage called brown …

Alternative splicing increases neuronal transcriptomic complexity throughout animal
phylogeny. To delve into the mechanisms controlling the assembly and evolution of this …

Aging is associated with increased risk of ocular disease, suggesting that age-associated
molecular changes in the eye increase its vulnerability to damage. Although there are …

Systemic glucose levels can be modulated with specific solar wavelengths that influence
mitochondrial metabolism. Mitochondrial respiration can be modulated using light that shifts …