Regulation and function of R-loops at repetitive elements
A Gambelli, A Ferrando, C Boncristiani, S Schoeftner - Biochimie, 2023 - Elsevier
R-loops are atypical, three-stranded nucleic acid structures that contain a stretch of RNA:
DNA hybrids and an unpaired, single stranded DNA loop. R-loops are physiological relevant …
DNA hybrids and an unpaired, single stranded DNA loop. R-loops are physiological relevant …
The regulation and immune signature of retrotransposons in cancer
MI Alkailani, D Gibbings - Cancers, 2023 - mdpi.com
Simple Summary A tiny human sample is enough to uncover the complete genome
sequence of that individual with the advances in biomedical technologies and data analysis …
sequence of that individual with the advances in biomedical technologies and data analysis …
On the interface of aging, cancer, and neurodegeneration with SIRT6 and L1 retrotransposon protein interaction network
J Nahálková - Ageing Research Reviews, 2024 - Elsevier
Roles of the sirtuins in aging and longevity appear related to their evolutionarily conserved
functions as retroviral-restriction factors. Retrotransposons also promote the aging process …
functions as retroviral-restriction factors. Retrotransposons also promote the aging process …
Integrative network analysis of differentially methylated regions to study the impact of gestational weight gain on maternal metabolism and fetal-neonatal growth
Integrative network analysis (INA) is important for identifying gene modules or epigenetically
regulated molecular pathways in diseases. This study evaluated the effect of excessive …
regulated molecular pathways in diseases. This study evaluated the effect of excessive …
Northern blotting of endogenous full-length human-specific LINE-1 RNA
MI Alkailani - Biology Methods and Protocols, 2024 - academic.oup.com
LINE-1 belongs to a family of DNA elements that move to new locations in the genome in a
process called “retrotransposition.” This is achieved by a copy-and-paste mechanism with …
process called “retrotransposition.” This is achieved by a copy-and-paste mechanism with …