Chitin is a major component of the exoskeleton and the peritrophic matrix of insects. It forms
complex structures in association with different assortments of cuticle and peritrophic matrix …

Genetic information flows from DNA to macromolecular structures—the dominant force in the
molecular organization of life. However, recent work suggests that metabolite availability to …

Glycans are the major carbon sources available to the human colonic microbiota. Numerous
N-glycosylated proteins are found in the human gut, from both dietary and host sources …

N-Glycan branching in the medial-Golgi generates ligands for lattice-forming lectins (eg,
galectins) that regulate surface levels of glycoproteins including epidermal growth factor …

Abstract Two LC‐ESI‐MS methods for the analysis of antibody glycosylation are presented.
In the first approach, tryptic glycopeptides are separated by RP chromatography and …

The structural diversity of glycoprotein N-linked oligosaccharides is determined by the
expression and regulation of glycosyltransferase activities and by the availability of the …

Publisher Summary This chapter highlights some of the recent and important findings
obtained from studies conducted on the synthesis, structure, physical state, modification …

β-N-Acetylhexosaminidases (EC 3.2. 1.52, belonging to CAZy GH families 3, 20 and 84)
have recently gained a lot of attention, not only due to their implication in human physiology …

Quality by design (QbD) is a scheme for the development, manufacture, and approval of
pharmaceutical products. The end goal of QbD is to ensure product quality by building it into …

Recent studies have explored the function of N-linked glycosylation in the nervous system,
demonstrating essential roles of carbohydrate structures in neural development. The …