Marine natural products
Covering: 2020 This review covers the literature published in 2020 for marine natural
products (MNPs), with 757 citations (747 for the period January to December 2020) referring …
products (MNPs), with 757 citations (747 for the period January to December 2020) referring …
The role of HBV cccDNA in occult hepatitis B virus infection
P He, P Zhang, Y Fang, N Han, W Yang, Z Xia… - Molecular and Cellular …, 2023 - Springer
Occult hepatitis B virus (HBV) infection (OBI) refers to the presence of replication-competent
HBV DNA in the liver, with or without HBV DNA in the blood, in individuals who tested …
HBV DNA in the liver, with or without HBV DNA in the blood, in individuals who tested …
Substrate specificities and inhibition pattern of the solute carrier family 10 members NTCP, ASBT and SOAT
G Grosser, SF Müller, M Kirstgen, B Döring… - Frontiers in molecular …, 2021 - frontiersin.org
Three carriers of the solute carrier family SLC10 have been functionally characterized so far.
Na+/taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and the …
Na+/taurocholate cotransporting polypeptide NTCP is a hepatic bile acid transporter and the …
Briarane-type diterpenoids suppress osteoclastogenisis by regulation of Nrf2 and MAPK/NF-kB signaling pathway
J Meng, X Zhang, X Guo, W Cheng, X Qi, J Huang… - Bioorganic …, 2021 - Elsevier
Excess osteoclastic activity leads to an imbalance in bone remodeling and causes most
adult skeletal diseases. Natural products are a promising source to attenuate the …
adult skeletal diseases. Natural products are a promising source to attenuate the …
Role of sodium taurocholate cotransporting polypeptide (NTCP) in HBV-induced hepatitis: Opportunities for developing novel therapeutics
Z Zhang, Q Zhang, Y Zhang, Y Lou, L Ge… - Biochemical …, 2023 - Elsevier
Hepatitis B is an infectious disease caused by the HBV virus. It presents a significant
challenge for treatment due to its chronic nature and the potential for developing severe …
challenge for treatment due to its chronic nature and the potential for developing severe …
[HTML][HTML] Targeting NTCP for liver disease treatment: A promising strategy
X Tan, Y Xiang, J Shi, L Chen, D Yu - Journal of Pharmaceutical Analysis, 2024 - Elsevier
The sodium taurocholate co-transporting polypeptide (NTCP), a bile acids transporter, has
been identified as a new therapeutic target for the treatment of liver disease. This paper …
been identified as a new therapeutic target for the treatment of liver disease. This paper …
Effects of Marine Natural Products on Liver Diseases
Y Sun, Y Dong, X Cui, X Guo, J Zhang, C Yu, M Zhang… - Marine Drugs, 2024 - mdpi.com
The prevention and treatment of liver disease, a class of disease that seriously threatens
human health, has always been a hot topic of medical research. In recent years, with the in …
human health, has always been a hot topic of medical research. In recent years, with the in …
Hepatitis B doubly spliced protein (HBDSP) promotes hepatocellular carcinoma cell apoptosis via ETS1/GATA2/YY1-mediated p53 transcription
X Xu, L Zhang, G Ye, J Shi, Y Peng, F Xin, Y Lin… - Journal of …, 2023 - Am Soc Microbiol
Chronic hepatitis B virus (HBV) infection represents an important global public health
concern. The spliced variants generated by RNA splicing from 3.5-kb HBV pre-genomic …
concern. The spliced variants generated by RNA splicing from 3.5-kb HBV pre-genomic …
Current Status and Challenges in Anti-Hepatitis B Virus Agents Based on Inactivation/Inhibition or Elimination of Hepatitis B Virus Covalently Closed Circular DNA
AQ Zhuang, Y Chen, SM Chen, WC Liu, Y Li, WJ Zhang… - Viruses, 2023 - mdpi.com
There has been over half a century since the discovery of hepatitis B virus (HBV) to now, but
approximately 300 million patients with chronic hepatitis B (CHB) still live in the world …
approximately 300 million patients with chronic hepatitis B (CHB) still live in the world …
[HTML][HTML] Transcriptome wide functional analysis of HBx expressing human hepatocytes stimulated with endothelial cell cross-talk
Identification of genes dysregulated during the hepatitis B virus (HBV)-host cell interaction
adds to the understanding of underlying molecular mechanisms and aids in discovering …
adds to the understanding of underlying molecular mechanisms and aids in discovering …