Background Aortic aneurysms (AA) are pathological dilations of the aorta, associated with
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …

Abdominal aortic aneurysm (AAA) is a life-threatening disease associated with high
morbidity, and high mortality in the event of aortic rupture. Major advances in open surgical …

Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease. Immune-
mediated infiltration and a destruction of the aortic wall during AAA development plays …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the
detoxification of alcohol-derived acetaldehyde and endogenous aldehydes. The inactivating …

Abdominal aortic aneurysms (AAA) are characterized by extensive extracellular matrix
(ECM) fragmentation and inflammation. However, the mechanisms by which these events …

Background—Stiffening of the aortic wall is a phenomenon consistently observed in age and
in abdominal aortic aneurysm (AAA). However, its role in AAA pathophysiology is largely …

Background—Abdominal aortic aneurysm (AAA) formation is characterized by inflammation,
smooth muscle activation and matrix degradation. This study tests the hypothesis that CD4+ …

After a period of relative senescence in the field of vascular smooth muscle cell (VSMC)
research with particular regards to atherosclerosis, the last few years has witnessed a …

The mechanism by which trauma initiates healing remains unclear. Precise understanding
of these events may define interventions for accelerating healing that could be translated to …

Abdominal aortic aneurysm (AAA) is characterized by inflammatory cell infiltration,
extracellular matrix (ECM) degradation, and vascular smooth muscle cell (SMC) dysfunction …