Microbial biofilm: formation, architecture, antibiotic resistance, and control strategies

MA Rather, K Gupta, M Mandal - Brazilian Journal of Microbiology, 2021 - Springer
The assembly of microorganisms over a surface and their ability to develop resistance
against available antibiotics are major concerns of interest. To survive against harsh …

The dental plaque biofilm matrix

NS Jakubovics, SD Goodman… - Periodontology …, 2021 - Wiley Online Library
The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Beyond risk: bacterial biofilms and their regulating approaches

MH Muhammad, AL Idris, X Fan, Y Guo, Y Yu… - Frontiers in …, 2020 - frontiersin.org
Bacterial biofilms are complex surface attached communities of bacteria held together by
self-produced polymer matrixs mainly composed of polysaccharides, secreted proteins, and …

Microenvironment‐activated Nanozyme‐armed bacteriophages efficiently combat bacterial infection

L Jin, F Cao, Y Gao, C Zhang, Z Qian… - Advanced …, 2023 - Wiley Online Library
Bacterial infection is one of the greatest challenges to public health, requiring new
therapeutic methods. Herein, an innovative nanozyme‐armed phage (phage@ palladium …

[HTML][HTML] Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and alternative therapeutic strategies

Z Pang, R Raudonis, BR Glick, TJ Lin, Z Cheng - Biotechnology advances, 2019 - Elsevier
Pseudomonas aeruginosa is an opportunistic pathogen that is a leading cause of morbidity
and mortality in cystic fibrosis patients and immunocompromised individuals. Eradication of …

Phage therapy in the postantibiotic era

FL Gordillo Altamirano, JJ Barr - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Antibiotic resistance is arguably the biggest current threat to global health. An increasing
number of infections are becoming harder or almost impossible to treat, carrying high …

Gastrointestinal biofilms in health and disease

JP Motta, JL Wallace, AG Buret, C Deraison… - Nature Reviews …, 2021 - nature.com
Microorganisms colonize various ecological niches in the human habitat, as they do in
nature. Predominant forms of multicellular communities called biofilms colonize human …

Novel antimicrobial agents for combating antibiotic-resistant bacteria

RYK Chang, SC Nang, HK Chan, J Li - Advanced drug delivery reviews, 2022 - Elsevier
Antibiotic therapy has become increasingly ineffective against bacterial infections due to the
rise of resistance. In particular, ESKAPE pathogens (Enterococcus faecium, Staphylococcus …

Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …