Organ-on-a-chip platforms for studying drug delivery systems

NS Bhise, J Ribas, V Manoharan, YS Zhang… - Journal of Controlled …, 2014 - Elsevier
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems.
Organ-on-a-chip systems—microscale recapitulations of complex organ functions—promise …

Microfluidics‐based 3D cell culture models: Utility in novel drug discovery and delivery research

N Gupta, JR Liu, B Patel, DE Solomon… - Bioengineering & …, 2016 - Wiley Online Library
The implementation of microfluidic devices within life sciences has furthered the possibilities
of both academic and industrial applications such as rapid genome sequencing, predictive …

Concentration gradient generation methods based on microfluidic systems

X Wang, Z Liu, Y Pang - RSC advances, 2017 - pubs.rsc.org
Various concentration gradient generation methods based on microfluidic systems are
summarized in this paper. The review covers typical structural characteristics, gradient …

Microfluidic cell culture systems for drug research

MH Wu, SB Huang, GB Lee - Lab on a Chip, 2010 - pubs.rsc.org
In pharmaceutical research, an adequate cell-based assay scheme to efficiently screen and
to validate potential drug candidates in the initial stage of drug discovery is crucial. In order …

Microfluidic tools for cell biological research

G Velve-Casquillas, M Le Berre, M Piel, PT Tran - Nano today, 2010 - Elsevier
Microfluidic technology is creating powerful tools for cell biologists to control the complete
cellular microenvironment, leading to new questions and new discoveries. We review here …

Review on cell mechanics: experimental and modeling approaches

ML Rodriguez, PJ McGarry… - Applied …, 2013 - asmedigitalcollection.asme.org
The interplay between the mechanical properties of cells and the forces that they produce
internally or that are externally applied to them play an important role in maintaining the …

Micro-sized microbial fuel cell: a mini-review

HY Wang, A Bernarda, CY Huang, DJ Lee… - Bioresource …, 2011 - Elsevier
This review presents the development of micro-sized microbial fuel cells (including mL-scale
and μL-scale setups), with summarization of their advantageous characteristics, fabrication …

A review of chemical gradient systems for cell analysis

H Somaweera, A Ibraguimov, D Pappas - Analytica chimica acta, 2016 - Elsevier
Microfluidic spatial and temporal gradient generators have played an important role in many
biological assays such as in the analysis of wound healing, inflammation, and cancer …

A review on microfluidics manipulation of the extracellular chemical microenvironment and its emerging application to cell analysis

P Chen, S Li, Y Guo, X Zeng, BF Liu - Analytica Chimica Acta, 2020 - Elsevier
Spatiotemporal manipulation of extracellular chemical environments with simultaneous
monitoring of cellular responses plays an essential role in exploring fundamental biological …

Microfluidics as a functional tool for cell mechanics

SA Vanapalli, MHG Duits, F Mugele - Biomicrofluidics, 2009 - pubs.aip.org
Living cells are a fascinating demonstration of nature's most intricate and well-coordinated
micromechanical objects. They crawl, spread, contract, and relax—thus performing a …