Apolipoprotein (a), an enigmatic anti-angiogenic glycoprotein in human plasma: A curse or cure?
V Kalaivani, A Jaleel - Pharmacological research, 2020 - Elsevier
Angiogenesis is a finely co-ordinated, multi-step developmental process of the new vascular
structure. Even though angiogenesis is regularly occurring in physiological events such as …
structure. Even though angiogenesis is regularly occurring in physiological events such as …
O‐glycan structures in apo (a) subunit of human lipoprotein (a) suppresses the pro‐angiogenic activity of galectin‐1 on human umbilical vein endothelial cells
Abstract Apolipoprotein (a)[apo (a)] is a highly polymorphic O‐glycoprotein circulating in
human plasma as lipoprotein (a)[Lp (a)]. The O‐glycan structures of apo (a) subunit of Lp (a) …
human plasma as lipoprotein (a)[Lp (a)]. The O‐glycan structures of apo (a) subunit of Lp (a) …
Circulating Lp (a): LDL complexes contain LDL molecules proportionate to Lp (a) size and bind to galectin-1: a possible route for LDL entry into cells
V Kalaivani, PS Appukuttan - Lipids, 2014 - Springer
The molecular mechanism of vascular pathology mediated by circulating lipoprotein (a)[Lp
(a)] remains unknown. We examined the role of two distinguishing features of Lp (a) viz non …
(a)] remains unknown. We examined the role of two distinguishing features of Lp (a) viz non …
Antigen-induced activation of antibody measured by fluorescence enhancement of FITC Label at Fc
G George, M Geetha, PS Appukuttan - Journal of fluorescence, 2015 - Springer
Three anti-carbohydrate antibodies of defined specificity isolated from plasma were used to
demonstrate that macromolecular antigen binding caused considerable enhancement of …
demonstrate that macromolecular antigen binding caused considerable enhancement of …
Immunopathology of desialylation: human plasma lipoprotein (a) and circulating anti-carbohydrate antibodies form immune complexes that recognize host cells
PS Sabarinath, PS Appukuttan - Molecular and cellular biochemistry, 2015 - Springer
Human plasma lipoprotein (a)[Lp (a)], the dominant lipoprotein in atherosclerotic plaques,
contains an apo (a) subunit of variable size linked to the apoB subunit of a low-density …
contains an apo (a) subunit of variable size linked to the apoB subunit of a low-density …
High glucose removes natural anti-α-galactoside and anti-β-glucoside antibody immune complexes adhering to surface O-glycoproteins of normal platelets and …
S Karthi, S Sukumari-Ramesh… - Experimental and …, 2022 - spandidos-publications.com
Human natural anti-α-galactoside (anti-Gal) and anti-β-glucoside (ABG) antibodies were
previously reported to recognize the serine-and threonine-rich peptide sequences (STPS) of …
previously reported to recognize the serine-and threonine-rich peptide sequences (STPS) of …
Anti-α-galactoside and anti-β-glucoside antibodies are partially occupied by either of two albumin-bound O-glycoproteins and circulate as ligand-binding triplets
K Sreedevi, SP Subramanian… - Immunological …, 2019 - Taylor & Francis
Two heavily O-glycosylated proteins and albumin co-purified with anti-α-galactoside (anti-
Gal), the chief xenograft-rejecting antibody and anti-β-glucan (ABG) antibody isolated from …
Gal), the chief xenograft-rejecting antibody and anti-β-glucan (ABG) antibody isolated from …
Activity of MUC1 cancer antigen-binding plasma anti-α-galactoside antibody correlates inversely with size of autologous lipoprotein (a)
J John, V Kalaivani, M Geetha… - … Biology and Medicine, 2019 - journals.sagepub.com
Variation in ligand-binding affinity of natural plasma anti-α-galactoside antibody (anti-Gal) is
a plausible reason for differing anti-cancer defense among individuals since serine-and …
a plausible reason for differing anti-cancer defense among individuals since serine-and …
Plasma anti-α-galactoside antibody mediates lipoprotein (a) binding to macrophages
B Sheela, G George, G Mandagini… - Glycoconjugate …, 2016 - Springer
Abstract Lipoprotein (a)[Lp (a)] is the dominant lipid in atherosclerotic plaques though it is
much less numerous than LDL or HDL in circulation. Molecular mechanism of selective …
much less numerous than LDL or HDL in circulation. Molecular mechanism of selective …
[HTML][HTML] Possible molecular basis for macromolecular antigen attachment to host cells: their immune complex with plasma antibodies have unoccupied binding sites …
G George, SK Chellappan, M Geetha… - AIMS Molecular …, 2017 - aimspress.com
Macromolecules such as lipoprotein (a) and antigens of Streptococcus mutans that cause
dental infections accumulate in perivascular cells in inflammatory vascular disorders though …
dental infections accumulate in perivascular cells in inflammatory vascular disorders though …