Clinical considerations for medication-related osteonecrosis of the jaw: a comprehensive literature review

M Kawahara, S Kuroshima, T Sawase - International journal of implant …, 2021 - Springer
Background Medication-related osteonecrosis of the jaw (MRONJ), which was first reported
as bisphosphonate-related osteonecrosis of the jaw (BRONJ) in bisphosphonate users, is a …

Medication-related osteonecrosis of the jaw: A literature review

S Kuroshima, M Sasaki, T Sawase - Journal of oral biosciences, 2019 - Elsevier
Background Antiresorptive agents such as bisphosphonates and denosumab, as well as
angiogenesis inhibitors, may induce medication-related osteonecrosis of the jaw (MRONJ) …

Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Biomaterials for craniofacial bone engineering

R Tevlin, A McArdle, D Atashroo… - Journal of dental …, 2014 - journals.sagepub.com
Conditions such as congenital anomalies, cancers, and trauma can all result in devastating
deficits of bone in the craniofacial skeleton. This can lead to significant alteration in function …

Medication‐related osteonecrosis of the jaw: a literature review and update

S Kuroshima, FA Al‐Omari, M Sasaki, T Sawase - Genesis, 2022 - Wiley Online Library
Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …

Osteonecrosis of the jaws (ONJ) in mice after extraction of teeth with periradicular disease

A Soundia, D Hadaya, N Esfandi, RS de Molon… - Bone, 2016 - Elsevier
Osteonecrosis of the jaws (ONJ) is a complication of antiresorptive medications, such as
denosumab or bisphosphonates, prescribed to patients with bone malignancy or …

Pathophysiology of Medication‐Related Osteonecrosis of the Jaw—A Minireview

S Tetradis, MR Allen, SL Ruggiero - Journal of Bone and Mineral …, 2023 - academic.oup.com
Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse effect of
antiresorptive medications administered for control of osseous malignancy, osteoporosis, or …

Spontaneous osteonecrosis of the jaws in the maxilla of mice on antiresorptive treatment: a novel ONJ mouse model

RS de Molon, S Cheong, O Bezouglaia, SM Dry, F Pirih… - Bone, 2014 - Elsevier
Although osteonecrosis of the jaws (ONJ), a serious complication of antiresorptive
medications, was reported a decade ago, the exact mechanisms of disease pathophysiology …

Transplantation of Noncultured Stromal Vascular Fraction Cells of Adipose Tissue Ameliorates Osteonecrosis of the Jaw–Like Lesions in Mice

S Kuroshima, M Sasaki, K Nakajima… - Journal of bone and …, 2018 - academic.oup.com
The precise pathoetiology and effective treatment strategies for bisphosphonate‐related
osteonecrosis of the jaw (BRONJ) remain unknown. Transplantation of noncultured stromal …

Rodents as an animal model for studying tooth extraction-related medication-related osteonecrosis of the jaw: assessment of outcomes

H Hadad, HR Matheus, SI Pai, FA Souza… - Archives of Oral …, 2023 - Elsevier
Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …