Silicosis is a fibrotic lung disease caused by inhalation of free crystalline silicon dioxide or
silica. Occupational exposure to respirable crystalline silica dust particles occurs in many …

“Silica” refers to crystalline particles formed by the combination of silicon with oxygen.
Inhalation of silica particles promotes the development of pulmonary fibrosis that over …

Humans are regularly exposed to silica nanoparticles in environmental and occupational
contexts, and these exposures have been implicated in the onset of adverse health effects …

Silicosis is the most common pneumoconiosis globally, with higher prevalence and
incidence in developing countries. To date, there is no effective treatment to halt or reverse …

In vitro three-dimensional (3D) lung cell models have been thoroughly investigated in recent
years and provide a reliable tool to assess the hazard associated with nanomaterials (NMs) …

Synthetic oligodeoxynucleotides (ODNs) comprised of the immunosuppressive motif
TTAGGG block TLR9 signaling, prevent STAT1 and STAT4 phosphorylation and attenuate a …

In addition to its roles in controlling infection and tissue repair, inflammation plays a critical
role in diverse and distinct chronic diseases, such as cancer, metabolic syndrome, and …

Allergic asthma is an airway disease, characterized by reversible bronchoconstriction,
chronic inflammation of the airway, and thickness of smooth muscle in the respiratory tract …

Wound healing is mediated through complex interactions between circulating immune cells
and local epithelial and endothelial cells. Elements of the innate immune system are …

Telomere shortening accompanies mammalian aging in vivo, and the burden of senescent
cells with short telomeres and a senescence-associated secretory phenotype (SASP) …