The emergence of 2-oxoglutarate as a master regulator metabolite

LF Huergo, R Dixon - Microbiology and Molecular Biology …, 2015 - Am Soc Microbiol
The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …

Sizing up metatranscriptomics

MA Moran, B Satinsky, SM Gifford, H Luo… - The ISME …, 2013 - academic.oup.com
A typical marine bacterial cell in coastal seawater contains only∼ 200 molecules of mRNA,
each of which lasts only a few minutes before being degraded. Such a surprisingly small …

Phage-specific metabolic reprogramming of virocells

C Howard-Varona, MM Lindback, GE Bastien… - The ISME …, 2020 - academic.oup.com
Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …

The global, ppGpp‐mediated stringent response to amino acid starvation in Escherichia coli

MF Traxler, SM Summers, HT Nguyen… - Molecular …, 2008 - Wiley Online Library
The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed
in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone …

Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry

SU Bajad, W Lu, EH Kimball, J Yuan, C Peterson… - … of chromatography A, 2006 - Elsevier
A key unmet need in metabolomics is the ability to efficiently quantify a large number of
known cellular metabolites. Here we present a liquid chromatography (LC)–electrospray …

[HTML][HTML] Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses

K Shimizu - Metabolites, 2013 - mdpi.com
An overview was made to understand the regulation system of a bacterial cell such as
Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate …

Nitric oxide: a neglected driver for the conjugative transfer of antibiotic resistance genes among wastewater microbiota

H Huang, G Feng, M Wang, C Liu, Y Wu… - Environmental …, 2022 - ACS Publications
The dissemination of plasmid-borne antibiotic resistance genes (ARGs) in wastewater is
becoming an urgent concern. Previous studies mainly focused on the effects of coexisting …

[HTML][HTML] Virus-associated organosulfur metabolism in human and environmental systems

K Kieft, AM Breister, P Huss, AM Linz, E Zanetakos… - Cell reports, 2021 - cell.com
Viruses influence the fate of nutrients and human health by killing microorganisms and
altering metabolic processes. Organosulfur metabolism and biologically derived hydrogen …

IscR‐dependent gene expression links iron‐sulphur cluster assembly to the control of O2‐regulated genes in Escherichia coli

JL Giel, D Rodionov, M Liu, FR Blattner… - Molecular …, 2006 - Wiley Online Library
IscR is an iron‐sulphur (Fe‐S) cluster‐containing transcription factor that represses
transcription of the operon containing its own gene and the iscSUA‐hscBA‐fdx genes …

Genome-Wide Transcriptional Responses of Escherichia coli K-12 to Continuous Osmotic and Heat Stresses

TS Gunasekera, LN Csonka, O Paliy - Journal of bacteriology, 2008 - Am Soc Microbiol
Osmotic stress is known to increase the thermotolerance and oxidative-stress resistance of
bacteria by a mechanism that is not adequately understood. We probed the cross-regulation …