The emergence of 2-oxoglutarate as a master regulator metabolite
The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …
Sizing up metatranscriptomics
A typical marine bacterial cell in coastal seawater contains only∼ 200 molecules of mRNA,
each of which lasts only a few minutes before being degraded. Such a surprisingly small …
each of which lasts only a few minutes before being degraded. Such a surprisingly small …
Phage-specific metabolic reprogramming of virocells
Ocean viruses are abundant and infect 20–40% of surface microbes. Infected cells, termed
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …
virocells, are thus a predominant microbial state. Yet, virocells and their ecosystem impacts …
The global, ppGpp‐mediated stringent response to amino acid starvation in Escherichia coli
MF Traxler, SM Summers, HT Nguyen… - Molecular …, 2008 - Wiley Online Library
The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed
in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone …
in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone …
Separation and quantitation of water soluble cellular metabolites by hydrophilic interaction chromatography-tandem mass spectrometry
SU Bajad, W Lu, EH Kimball, J Yuan, C Peterson… - … of chromatography A, 2006 - Elsevier
A key unmet need in metabolomics is the ability to efficiently quantify a large number of
known cellular metabolites. Here we present a liquid chromatography (LC)–electrospray …
known cellular metabolites. Here we present a liquid chromatography (LC)–electrospray …
[HTML][HTML] Regulation Systems of Bacteria such as Escherichia coli in Response to Nutrient Limitation and Environmental Stresses
K Shimizu - Metabolites, 2013 - mdpi.com
An overview was made to understand the regulation system of a bacterial cell such as
Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate …
Escherichia coli in response to nutrient limitation such as carbon, nitrogen, phosphate …
Nitric oxide: a neglected driver for the conjugative transfer of antibiotic resistance genes among wastewater microbiota
H Huang, G Feng, M Wang, C Liu, Y Wu… - Environmental …, 2022 - ACS Publications
The dissemination of plasmid-borne antibiotic resistance genes (ARGs) in wastewater is
becoming an urgent concern. Previous studies mainly focused on the effects of coexisting …
becoming an urgent concern. Previous studies mainly focused on the effects of coexisting …
[HTML][HTML] Virus-associated organosulfur metabolism in human and environmental systems
Viruses influence the fate of nutrients and human health by killing microorganisms and
altering metabolic processes. Organosulfur metabolism and biologically derived hydrogen …
altering metabolic processes. Organosulfur metabolism and biologically derived hydrogen …
IscR‐dependent gene expression links iron‐sulphur cluster assembly to the control of O2‐regulated genes in Escherichia coli
JL Giel, D Rodionov, M Liu, FR Blattner… - Molecular …, 2006 - Wiley Online Library
IscR is an iron‐sulphur (Fe‐S) cluster‐containing transcription factor that represses
transcription of the operon containing its own gene and the iscSUA‐hscBA‐fdx genes …
transcription of the operon containing its own gene and the iscSUA‐hscBA‐fdx genes …
Genome-Wide Transcriptional Responses of Escherichia coli K-12 to Continuous Osmotic and Heat Stresses
TS Gunasekera, LN Csonka, O Paliy - Journal of bacteriology, 2008 - Am Soc Microbiol
Osmotic stress is known to increase the thermotolerance and oxidative-stress resistance of
bacteria by a mechanism that is not adequately understood. We probed the cross-regulation …
bacteria by a mechanism that is not adequately understood. We probed the cross-regulation …