Structural insights into SARS-CoV-2 proteins

R Arya, S Kumari, B Pandey, H Mistry, SC Bihani… - Journal of molecular …, 2021 - Elsevier
The unprecedented scale of the ongoing COVID-19 pandemic has catalyzed an intense
effort of the global scientific community to unravel different aspects of the disease in a short …

SARS-CoV-2 mutations and their viral variants

B Cosar, ZY Karagulleoglu, S Unal, AT Ince… - Cytokine & growth factor …, 2022 - Elsevier
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …

[HTML][HTML] Structural basis for SARS-CoV-2 envelope protein recognition of human cell junction protein PALS1

J Chai, Y Cai, C Pang, L Wang, S McSweeney… - Nature …, 2021 - nature.com
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has created global health and
economic emergencies. SARS-CoV-2 viruses promote their own spread and virulence by …

[HTML][HTML] SARS-CoV-2 accessory proteins reveal distinct serological signatures in children

A Hachim, H Gu, O Kavian, M Mori, MYW Kwan… - Nature …, 2022 - nature.com
The antibody response magnitude and kinetics may impact clinical severity, serological
diagnosis and long-term protection of COVID-19, which may play a role in why children …

[HTML][HTML] Approaches towards fighting the COVID‑19 pandemic

SC Tsai, CC Lu, DT Bau, YJ Chiu… - International …, 2021 - spandidos-publications.com
Abstract The coronavirus disease 2019 (COVID‑19) outbreak, which has caused> 46
millions confirmed infections and> 1.2 million coronavirus related deaths, is one of the most …

[HTML][HTML] Emerging SARS-CoV-2 variants: a review of its mutations, its implications and vaccine efficacy

S Ramesh, M Govindarajulu, RS Parise, L Neel… - Vaccines, 2021 - mdpi.com
The widespread increase in multiple severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) variants is causing a significant health concern in the United States and …

Mutational insights into the envelope protein of SARS-CoV-2

MS Rahman, MN Hoque, MR Islam, I Islam, ID Mishu… - Gene reports, 2021 - Elsevier
The ongoing mutations in the structural proteins of SARS-CoV-2 are the major impediment
for prevention and control of the COVID-19 disease. Presently we focused on evolution of …

The envelope protein of SARS‐CoV‐2 increases intra‐Golgi pH and forms a cation channel that is regulated by pH

D Cabrera‐Garcia, R Bekdash… - The Journal of …, 2021 - Wiley Online Library
Key points We report a novel method for the transient expression of SARS‐CoV‐2 envelope
(E) protein in intracellular organelles and the plasma membrane of mammalian cells and …

[HTML][HTML] SARS-CoV-2 Envelope (E) protein interacts with PDZ-domain-2 of host tight junction protein ZO1

A Shepley-McTaggart, CA Sagum, I Oliva… - PLoS …, 2021 - journals.plos.org
Newly emerged SARS-CoV-2 is the cause of an ongoing global pandemic leading to severe
respiratory disease in humans. SARS-CoV-2 targets epithelial cells in the respiratory tract …

Host PDZ‐containing proteins targeted by SARS‐CoV‐2

C Caillet‐Saguy, F Durbesson, VV Rezelj… - The FEBS …, 2021 - Wiley Online Library
Small linear motifs targeting protein interacting domains called PSD‐95/Dlg/ZO‐1 (PDZ)
have been identified at the C terminus of the severe acute respiratory syndrome coronavirus …