A new series of antibacterial pyrazolo-triazolo-pyrimidine derivatives 3a-3i were synthesized
in two steps starting from aminopyrazole 1 and characterized by 1 H NMR 13 C NMR and …

A novel series of 6-aryl-3-methyl-1-phenyl-1H-pyrazolo [3, 4-d] pyrimidin-4 (5H)-ones 3a-h
were synthesized in a single step via condensation of carboxamide 2 with some aromatic …

Heterocyclic compounds have diverse structure, which makes them broad and economical
therapeutic agents. Pyrazole is a five-membered aromatic ring that contains two nitrogen …

Abstract Cyclin-dependent kinase 2 (CDK2) is a vital protein for controlling cell cycle
progression that is critically associated with various malignancies and its inhibition could …

The Dimroth Rearrangement in the Synthesis of Condensed Pyrimidines – Structural
Analogs of Antiviral Compounds | SpringerLink Skip to main content Advertisement …

Abstract The starting 3-(3, 5-dimethyl-1 H-pyrazol-1-yl)-3-oxopropanenitrile (1) reacts with
phenyl isothiocyanate and ethyl bromoacetate to give the corresponding thiazole derivative …

In the present study, a new series of Schiff bases (4a-h) were designed and synthesized via
the treatment of the previously prepared 5-aminopyrazolopyrimidinone 3 with a series of …

A series of novel pyrazole amide derivatives 3a–3p which take TMV PC protein as the target
has been designed and synthesized by the reactions of 5-chloro-1-aryl-3-methyl-1 H …

The target new hybrid molecule types pyrazolo [4, 3-e]-1, 2, 4-triazolo [1, 5-c] pyrimidines
phosphonates 4 and 2-(coumarin-3''-yl)-7-phenylpyrazolo [4, 3-e]-1, 2, 4-triazolo [1, 5-c] …

To explore a new set of anticancer agents, a novel series of pyrazolo [4, 3-e] pyrido [1, 2-a]
pyrimidine derivativeshave been designed and synthesized viacyclocondensation reactions …