Background Anxiety disorders are the most common neuropathologies worldwide, but the
precise neuronal mechanisms that underlie these disorders remain unknown. The …

The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure
induces long-term changes in baseline responses to anxiety-inducing environments, and if …

Mood-related disorders have a high prevalence among children and adolescents, posing a
public health challenge, given their adverse impact on these young populations. Treatment …

Background. Poststroke depression (PSD) is the most common and serious neuropsychiatric
complication occurring after cerebrovascular accidents, seriously endangering human …

Background Second messenger signaling within the mesolimbic reward circuit plays a key
role in the negative effects of stress and the underlying mechanisms that promote drug …

Background: Fluoxetine (FLX) represents the antidepressant of choice for the management
of pediatric mood-related illnesses. Accumulating preclinical evidence suggests that …

There has been a disproportionate increase in fluoxetine (FLX) prescription rates within the
juvenile population. Thus, we evaluated how adolescent FLX exposure alters expression …

Second-messenger signaling within the mesolimbic reward circuit is involved in both the
long-lived effects of stress and in the underlying mechanisms that promote drug abuse …

Background: Previous research has emphasized the negative impact of early maternal
deprivation on learning and memory. On the other hand, the role of training on cognition has …

Introduction: Stress is defined as a physiological response to environmental conditions
which could cause changes in the level of neuropeptides in the central nervous system …