In patients with decompensated cirrhosis, sarcopenia and frailty are prevalent. Although
several definitions exist for these terms, in the field of hepatology, sarcopenia has commonly …

Aging is a complex biological process characterized by hallmark features accumulating over
the life course, shaping the individual's aging trajectory and subsequent disease risks. There …

Frailty can be viewed as a state of physiological decline that increases susceptibility to
adverse health outcomes. This loss of physiological reserve means that even small stressors …

Abstract Purpose of Review Biological age is the concept of using biophysiological
measures to more accurately determine an individual's age-related risk of adverse …

Aging is a complex progression of changes best characterized as the chronic dysregulation
of cellular processes leading to deteriorated tissue and organ function. Although aging …

Ageing is an enigmatic and progressive biological process which undermines the normal
functions of living organisms with time. Ageing has been conspicuously linked to dietary …

Global average life expectancy continues to rise. As aging increases the likelihood of frailty,
which encompasses metabolic, musculoskeletal, and cognitive deficits, there is a need for …

The architectural specializations and targeted delivery pathways of cardiomyocytes ensure
that L-type Ca2+ channels (CaV1. 2) are concentrated on the t-tubule sarcolemma within …

Background Frailty is an important concept for risk stratification in clinical practice, but it is
hardly acknowledged at all in mental healthcare settings. This paper aims to assess the …

The hypothesis that pain can predispose to frailty development has been recently
investigated in several clinical studies suggesting that frailty and pain may share some …