Despite antiretroviral therapy (ART), people living with human immunodeficiency virus
(HIV)(PLWH) continue to experience chronic inflammation and immune dysfunction, which …

The female reproductive tract harbours hundreds of bacterial species and produces
numerous metabolites. The uterine cervix is located between the upper and lower parts of …

Human Immunodeficiency Virus (HIV) is still one of the major global health issues, and
despite significant efforts that have been put into studying the pathogenesis of HIV infection …

The human vaginal microbiota has a central role in the regulation of the female reproductive
tract (FRT) inflammation. Indeed, on one hand an optimal environment leading to a …

The vaginal microbiome (VMB) is critical to female reproductive health; however, the
mechanisms associated with optimal and non-optimal states remain poorly understood due …

Preventing new HIV infections remains a global challenge. Young women continue to bear a
disproportionate burden of infection. Oral pre-exposure prophylaxis (PrEP), offers a novel …

Background Bacterial vaginosis (BV) treatment failures and recurrences are common. To
identify features associated with treatment response, we compared vaginal microbiota and …

Women and girls represent a key population driving new HIV infections and persistence of
the HIV pandemic. A key determinant of HIV susceptibility is the composition of the vaginal …

Immunoglobulin G (IgG) antibodies that activate Fc-mediated immune functions have been
correlated with vaccine efficacy, but it is difficult to unravel the relative roles of multiple IgG …

Human immunodeficiency virus (HIV) infection and the ensuing acquired immunodeficiency
syndrome (AIDS) disproportionally affect young women, yet understanding of the factors …