Comprehensive review on the pathogenesis of hypertriglyceridaemia-associated acute pancreatitis

M Qiu, X Zhou, M Zippi, H Goyal, Z Basharat… - Annals of …, 2023 - Taylor & Francis
It is well known, that the inflammatory process that characterizes acute pancreatitis (AP) can
lead to both pancreatic damage and systemic inflammatory response syndrome (SIRS) …

Hypertriglyceridemia acute pancreatitis: animal experiment research

L Wang, T Xu, R Wang, X Wang, D Wu - Digestive diseases and sciences, 2022 - Springer
In recent years, the number of acute pancreatitis cases caused by hypertriglyceridemia has
increased gradually, which has caught the attention of the medical community. However …

Factors affecting outcome in acute hypertriglyceridemic pancreatitis treated with plasma exchange: an observational cohort study

J Gubensek, J Buturovic-Ponikvar, K Romozi… - PloS one, 2014 - journals.plos.org
Objectives The optimal therapy for hypertriglyceridemic acute pancreatitis, especially the
role of plasma exchange (PE), is not entirely clear. The aim of our large, single-center …

Therapeutic effects of quercetin on early inflammation in hypertriglyceridemia-related acute pancreatitis and its mechanism

JY Zheng, JH Wu, J Chen, J Liu, YY Lu, CL Huang… - Pancreatology, 2016 - Elsevier
Objective To investigate the therapeutic effects of quercetin on early-stage inflammation in
hypertriglyceridemia (HTG)-related acute pancreatitis (AP) both in vivo and in vitro, and its …

Double filtration plasma apheresis shortens hospital admission duration of patients with severe hypertriglyceridemia-associated acute pancreatitis

CT Chang, TY Tsai, HY Liao, CM Chang, JS Jheng… - Pancreas, 2016 - journals.lww.com
Objectives The treatment effectiveness of double filtration plasma apheresis (DFPP) on
severe hypertriglyceridemia-associated acute pancreatitis (STAP) has been questioned …

Development of a novel model of hypertriglyceridemic acute pancreatitis in mice

Y Pan, Y Li, L Gao, Z Tong, B Ye, S Liu, B Li, Y Chen… - Scientific Reports, 2017 - nature.com
The morbidity rate of hypertriglyceridemic acute pancreatitis (HTG-AP) increased rapidly
over the last decade. However an appropriate animal model was lacking to recapitulate this …

Animal models: challenges and opportunities to determine optimal experimental models of pancreatitis and pancreatic cancer

JL Saloman, KM Albers, Z Cruz-Monserrate, BM Davis… - Pancreas, 2019 - journals.lww.com
At the 2018 PancreasFest meeting, experts participating in basic research met to discuss the
plethora of available animal models for studying exocrine pancreatic disease. In particular …

Experimental models in syrian golden hamster replicate human acute pancreatitis

Y Wang, A Kayoumu, G Lu, P Xu, X Qiu, L Chen, R Qi… - Scientific reports, 2016 - nature.com
The hamster has been shown to share a variety of metabolic similarities with humans. To
replicate human acute pancreatitis with hamsters, we comparatively studied the efficacy of …

Probucol pharmacological and bio-nanotechnological effects on surgically transplanted graft due to powerful anti-inflammatory, anti-fibrotic and potential bile acid …

A Mooranian, CM Ionescu, SR Wagle, B Kovacevic… - Pharmaceutics, 2021 - mdpi.com
Introduction. A major obstacle in islet transplantation and graft survival pre and post
transplantation is islet apoptosis due to mainly inflammatory bio molecules released during …

Study on the mechanism of probucol nanosuspension on hyperlipidemic pancreatitis and regulation of blood lipid function

Z Wu, X Wang, X Jiang - Journal of nanoscience and …, 2021 - ingentaconnect.com
High-fat pancreatitis and hyperlipidemia refer to disorders of blood lipid metabolism caused
by abnormally elevated blood lipids, and are risk factors for high-risk diseases such as …