Activating innate immunity in a controlled manner is necessary for the development of next-
generation therapeutics. Adjuvants, or molecules that modulate the immune response, are …

Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …

Adjuvants and vaccine delivery systems are used widely to improve the efficacy of vaccines.
Their primary roles are to protect antigen from degradation and allow its delivery and uptake …

Yeast is an integral part of mammalian microbiome, and like commensal bacteria, has the
potential of being harnessed to influence immunity in clinical settings. However, functional …

Lipopolysaccharides (LPS) are the main components of the external leaflet of the Gram-
negative outer membrane and consist of three different moieties: lipid A, core …

Helicobacter pylori (H. pylori) is a recalcitrant pathogen, which can cause gastric disorders.
During the past decades, polypharmacy‐based regimens, such as triple and quadruple …

The urgent task of creating new, enhanced adjuvants is closely related to our
comprehension of their mechanisms of action. A few adjuvants have shown sufficient …

Carbohydrates are ubiquitous molecules expressed on the surface of nearly all living cells,
and their interaction with carbohydrate-binding proteins is critical to many immunobiological …

Future infectious disease outbreaks are inevitable; therefore, it is critical that we maximize
our readiness for these events by preparing effective public health policies and healthcare …

Adjuvants are essential components of modern vaccines. One general mechanism
underlying their immunostimulatory functions is the activation of pattern recognition …