The naked truth: a comprehensive clarification and classification of current 'myths' in naked mole‐rat biology

R Buffenstein, V Amoroso, B Andziak… - Biological …, 2022 - Wiley Online Library
The naked mole‐rat (Heterocephalus glaber) has fascinated zoologists for at least half a
century. It has also generated considerable biomedical interest not only because of its …

Animal models of human pregnancy and placentation: alternatives to the mouse

AM Carter - Reproduction, 2020 - rep.bioscientifica.com
The mouse is often criticized as a model for pregnancy research as gestation is short, with
much of organ development completed postnatally. There are also differences in the …

The idiosyncratic physiological traits of the naked mole-rat; a resilient animal model of aging, longevity, and healthspan

R Buffenstein, W Craft - The extraordinary biology of the naked mole-rat, 2021 - Springer
The subterranean-dwelling naked mole-rat (Heterocephalus glaber) is an extremophilic
rodent, able to thrive in the harsh underground conditions of sub-Saharan Northeast Africa …

Promoting validation and cross-phylogenetic integration in model organism research

KC Cheng, RD Burdine, ME Dickinson… - Disease models & …, 2022 - journals.biologists.com
Model organism (MO) research provides a basic understanding of biology and disease due
to the evolutionary conservation of the molecular and cellular language of life. MOs have …

Spontaneous disease and pathology of naked mole-rats

MA Delaney, DM Imai, R Buffenstein - … Biology of the Naked Mole-Rat, 2021 - Springer
Naked mole-rats are highly valuable research models and popular exhibition animals at
zoos worldwide. Here, we provide comprehensive descriptions of common postmortem …

relevant conditions and pathology of laboratory mice, rats, gerbils, Guinea pigs, hamsters, naked mole rats, and rabbits

TK Cooper, DK Meyerholz, AP Beck, MA Delaney… - ILAR …, 2021 - academic.oup.com
Animals are valuable resources in biomedical research in investigations of biological
processes, disease pathogenesis, therapeutic interventions, safety, toxicity, and …

Aging through an epitranscriptomic lens

M McMahon, C Forester, R Buffenstein - Nature Aging, 2021 - nature.com
The mechanistic causes of aging, the time-related decline in function and good health that
leads to increased mortality, remain poorly understood. Here we propose that age …

Opportunities for new insight into aging from the naked mole-rat and other non-traditional models

R Buffenstein, JG Ruby - Nature aging, 2021 - nature.com
Opportunities for new insight into aging from the naked mole-rat and other non-traditional models
| Nature Aging Skip to main content Thank you for visiting nature.com. You are using a browser …

The unusual immune system of the naked mole-rat

T Lin, R Buffenstein - The Extraordinary Biology of the Naked Mole-Rat, 2021 - Springer
The immune system plays a critical role in host defense to pathogens, tissue homeostasis,
cancer development, and several aging-associated chronic inflammatory diseases. The …

[HTML][HTML] Cholesterol-rich naked mole-rat brain lipid membranes are susceptible to amyloid beta-induced damage in vitro

D Frankel, M Davies, B Bhushan, Y Kulaberoglu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Naked mole-rats are extraordinarily long-lived rodents that offer unique opportunities to
study the molecular origins of age-related neurodegenerative diseases. Remarkably, they …