Precision medicine gives individuals tailored medical treatment, with the genotype
determining the therapeutic strategy, the appropriate dosage, and the likelihood of benefit or …

As costs of next-generation sequencing decrease, identification of genetic variants has far
outpaced our ability to understand their functional consequences. This lack of understanding …

Importance Pharmacogenomic (PGx) testing provides preemptive pharmacotherapeutic
guidance regarding the lack of therapeutic benefit or adverse drug reactions of PGx targeted …

Background Different levels of evidence related to the variable responses of individuals to
drug treatment have been reported in various pharmacogenomic (PGx) databases …

Genetic ancestry plays a major role in pharmacogenomics, and a deeper understanding of
the genetic diversity among individuals holds immerse promise for reshaping personalized …

Objective A wide variety of commercial pharmacogenetic (PGx) tools are available
worldwide to guide treatment selection for depression based on individuals' genetic profiles …

Some gene polymorphisms have been previously associated individually with tacrolimus
efficacy and toxicity, but no long-term study to determine the role of pharmacogene variants …

CYP2A6 is a very important enzyme that plays a crucial role in nicotine compounds and is
responsible for the metabolism of more than 3% drugs of total metabolized drugs by the CYP …

Purpose Our study genotyped pharmacogenes in 200 individuals from Inner Mongolia
Autonomous Region, China. Aim to find distinct pharmacogenomic variations among the …

Drugs pharmacology is defined by pharmacokinetics and pharmacodynamics and both of
them are affected by genetic variability. Genetic variability varies from population to …