Updates on triple-negative breast cancer in type 2 diabetes mellitus patients: from risk factors to diagnosis, biomarkers and therapy

S Matou-Nasri, M Aldawood, F Alanazi, AL Khan - Diagnostics, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is usually the most malignant and aggressive
mammary epithelial tumor characterized by the lack of expression for estrogen receptors …

Diabetes in China part 2: prevention, challenges, and progress

Y Xu, J Lu, M Li, T Wang, K Wang, Q Cao… - The Lancet Public …, 2024 - thelancet.com
During the past 40 years, the prevalence of diabetes in China has increased from less than
1· 0% in 1980 to 12· 4% in 2018, an increase in line with the rapid growth of the nation's …

Cost-effectiveness of expanded antiviral treatment for chronic hepatitis B virus infection in China: an economic evaluation

S Zhang, C Wang, B Liu, QB Lu, J Shang… - The Lancet Regional …, 2023 - thelancet.com
Background China, which has the largest chronic hepatitis B virus (HBV) burden, may
expand antiviral therapy to attain the World Health Organization (WHO)-2030 goal of 65 …

Investigation on the inhibition mechanism and binding behavior of cryptolepine to α-glucosidase and its hypoglycemic activity by multi-spectroscopic method

X Min, S Guo, Y Lu, X Xu - Journal of Luminescence, 2024 - Elsevier
Cryptolepine, one important active ingredient of Cryptolepis sanguinolenta (Lour), exhibits
various beneficial pharmacological activities. But its anti-α-glucosidase and hypoglycemic …

Cost-effectiveness of artificial intelligence-assisted liquid-based cytology testing for cervical cancer screening in China

M Shen, Z Zou, H Bao, CK Fairley, K Canfell… - The Lancet Regional …, 2023 - thelancet.com
Summary Background The 2021 World Health Organization (WHO) guidelines for cervical
cancer screening recommend human papillomavirus (HPV) DNA or mRNA testing. Artificial …

Detection of diabetic patients in people with normal fasting glucose using machine learning

K Lv, C Cui, R Fan, X Zha, P Wang, J Zhang, L Zhang… - BMC medicine, 2023 - Springer
Background Diabetes mellitus (DM) is a chronic metabolic disease that could produce
severe complications threatening life. Its early detection is thus quite important for the timely …

Exposure to cadmium and lead is associated with diabetic kidney disease in diabetic patients

Y Zhang, X Gong, R Li, W Gao, D Hu, X Yi, Y Liu… - Environmental …, 2024 - Springer
Abstract Background Cadmium (Cd) and lead (Pb) exhibit nephrotoxic activity and may
accelerate kidney disease complications in diabetic patients, but studies investigating the …

Global burden and drivers of hyperglycemia: Estimates and predictions from 1990 to 2050

HL Qiu, S Fan, K Zhou, Z He, MHEM Browning… - The Innovation, 2023 - cell.com
Hyperglycemia is a key risk factor for death and disability worldwide. To better inform
prevention strategies, we aimed to delineate and predict the temporal, spatial, and …

Metformin improves cognitive dysfunction through SIRT1/NLRP3 pathway–mediated neuroinflammation in db/db mice

T Hu, JW Wei, JY Zheng, QY Luo, XR Hu, Q Du… - Journal of Molecular …, 2024 - Springer
Diabetes mellitus (DM), an important public health problem, aggravates the global economic
burden. Diabetic encephalopathy (DE) is a serious complication of DM in the central …

Dihydromyricetin ameliorates diabetic renal fibrosis via regulating SphK1 to suppress the activation of NF-κB pathway

M Wen, X Sun, L Pan, S Jing, X Zhang, L Liang… - European Journal of …, 2024 - Elsevier
Dihydromyricetin (DHM) is a flavonoid from vine tea with broad pharmacological benefits,
which improve inflammation by blocking the NF-κB pathway. A growing body of research …