Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement

J Herrmann, D Lenihan, S Armenian… - European heart …, 2022 - academic.oup.com
Abstract The discipline of Cardio-Oncology has seen tremendous growth over the past
decade. It is devoted to the cardiovascular (CV) care of the cancer patient, especially to the …

Cardiovascular immunotoxicities associated with immune checkpoint inhibitors: a safety meta-analysis

C Dolladille, J Akroun, PM Morice… - European Heart …, 2021 - academic.oup.com
Aims The risk and incidence of cardiovascular (CV) immune-related adverse events (irAEs)
associated with immune checkpoint inhibitors (ICIs) in cancer patients remain unknown …

Cardiovascular complications of immune checkpoint inhibitors for cancer

F Thuny, J Naidoo, TG Neilan - European heart journal, 2022 - academic.oup.com
Over the last decade or so, there has been a paradigm shift in the oncologic care of patients
with a range of solid tumour and haematologic malignancies, away from traditional cytotoxic …

Electrocardiographic manifestations of immune checkpoint inhibitor myocarditis

JR Power, J Alexandre, A Choudhary, B Ozbay… - Circulation, 2021 - Am Heart Assoc
A retrospective multicenter registry including 49 institutions and 11 countries was built using
a Research Electronic Data Capture web-based platform with Institutional Review Board …

[HTML][HTML] Ventricular arrhythmia in cancer patients: mechanisms, treatment strategies and future avenues

MA Agarwal, A Sridharan, RC Pimentel… - Arrhythmia & …, 2023 - ncbi.nlm.nih.gov
Cardiovascular disease and cancer are the leading causes of morbidity and mortality in the
US. Despite the significant progress made in cancer treatment leading to improved …

Mediators and mechanisms of immune checkpoint inhibitor‐associated myocarditis: Insights from mouse and human

J Gong, TG Neilan, DA Zlotoff - Immunological Reviews, 2023 - Wiley Online Library
The broad application of immune checkpoint inhibitors (ICIs) has led to significant gains in
cancer outcomes. By abrogating inhibitory signals, ICIs promote T cell targeting of cancer …

Longitudinal strain and troponin I elevation in patients undergoing immune checkpoint inhibitor therapy

Y Tamura, Y Tamura, R Takemura, K Yamada… - Cardio Oncology, 2022 - jacc.org
Abstract Background Immune checkpoint inhibitors (ICIs) are a central part of cancer
therapy; however, cardiac complications, such as myocarditis, have the potential for …

[HTML][HTML] Electrocardiographic features of immune checkpoint inhibitor-associated myocarditis

W Song, Y Zheng, M Dong, L Zhong, G Bazoukis… - Current Problems in …, 2023 - Elsevier
Immune checkpoint inhibitors (ICIs) are associated with immune-related adverse events
including myocarditis, whilst improving cancer-related outcomes. There is thus a clinical …

Case Report: Treatment for steroid-refractory immune-related myocarditis with tofacitinib

Q Xing, Z Zhang, B Zhu, Q Lin, L Shen, F Li… - Frontiers in …, 2022 - frontiersin.org
Introduction Immune therapy has ushered in a new era of tumor treatment, at the expense of
immune-related adverse events, including rare but fatal adverse cardiovascular events, such …

Multi-organ immune-related adverse event is a risk factor of immune checkpoint inhibitor-associated myocarditis in cancer patients: a multi-center study

X Xie, L Wang, Y Li, Y Xu, J Wu, X Lin, W Lin… - Frontiers in …, 2022 - frontiersin.org
Background and Objective Immune checkpoint inhibitor (ICI)-associated myocarditis is a
fatal immune-related adverse events (irAEs), which is prone to affecting multiple organ …